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World Neurosurg
Department of Neurosurgery, University of Arkansas for Medical Science, Arkansas Children's Hospital, Little Rock, Arkansas, USA. Electronic address:
Published: January 2018
Background: The most common neurologic manifestations of fibrous dysplasia (FD) are vision and hearing loss. Optic decompression for progressive vision loss has been shown to yield positive results in terms of visual outcomes; however, emergency optic decompression surgery for sudden loss of vision in FD has not to date been reported in the pediatric population. We report the first case of FD presenting with sudden vision loss and successfully managed with emergency optic decompression.
Case Description: A 10-year-old male patient known to have FD with a 2-month history of progressive vision loss in his left eye presents with sudden blindness. Emergency decompression surgery restored vision in his left eye to 20/40, which remained stable on long-term follow-up.
Conclusion: There is no consensus on the benefit and safety of prophylactic optic decompression, yet therapeutic decompression has been shown to prevent vision deterioration. Our findings suggest that therapeutic decompression even when done in the emergency setting yields positive results, while prophylactic decompression carries an inherent risk for loss of vision in a seeing eye.
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http://dx.doi.org/10.1016/j.wneu.2017.09.119 | DOI Listing |
Sci Rep
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State Key Laboratory of Ophthalmology, Optometry and Vision Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China, 325000.
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Department of Medicine, Vanderbilt University School of Medicine, 2215 Garland Ave, Nashville, TN, 37232, USA.
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Department of Ophthalmology, University of Washington, Seattle, Washington; Roger and Angie Karalis Johnson Retina Center, Seattle, Washington. Electronic address:
Age-related macular degeneration (AMD), a leading cause of vision loss among older adults, affecting more than 200 million people worldwide. With no cure currently available and a rapidly increasing prevalence, emerging approaches such as artificial intelligence (AI) and machine learning (ML) hold promise for advancing the study of AMD. The effective utilization of AI and ML in AMD research is highly dependent on access to high-quality and reusable clinical data.
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March 2025
Birla Institute of Technology & Science Pilani - K K Birla Goa Campus, Department of Chemistry, NH 17 B Bypass Road, 403726, Zuarinagar, INDIA.
Polydiacetylenes (PDAs) have emerged as a promising class of stimuli-responsive materials due to their unique blue-to-red chromatic transition and associated fluorescence turn-on effect. These optical properties arise from the topochemical polymerization of diacetylene monomers into highly conjugated π-electron systems, enabling PDAs to function as dual-mode sensors. Their colorimetric and fluorimetric responses to external stimuli, including temperature, pH, mechanical stress, and chemical or biological interactions, have been widely exploited for sensing applications.
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