This study numerically and experimentally investigates a photonic approach for microwave time delay, which takes advantage of the redshift of the laser cavity resonance induced by external optical injection in a semiconductor laser. The strong enhancement around the redshifted cavity resonance not only amplifies the power, but also shifts the phase of the microwave signals carried by the optical injection. Such a microwave phase shift is approximately linear over a few gigahertz, leading to a constant microwave time delay over the frequency range. A different time delay can be achieved by simply adjusting the injection power or frequency. For the microwave frequencies up to 40 GHz investigated in this Letter, a continuously tunable range of more than 80 ps in time delay is achieved over an instantaneous bandwidth of approximately 7 GHz. The quality of the data carried by the microwave signals is mostly preserved after time delay. Thus, a bit-error ratio down to 10 at 2.5 Gb/s is achieved with a possible detection sensitivity improvement of 5 dB.
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http://dx.doi.org/10.1364/OL.42.003307 | DOI Listing |
J Clin Oncol
January 2025
Institute of Cancer Research, London, United Kingdom.
Purpose: Transurethral resection of bladder tumor (TURBT) is the initial staging procedure for new bladder cancers (BCs). For muscle-invasive bladder cancers (MIBCs), TURBT may delay definitive treatment. We investigated whether definitive treatment can be expedited for MIBC using flexible cystoscopic biopsy and multiparametric magnetic resonance imaging (mpMRI) for initial staging.
View Article and Find Full Text PDFJ Neuroophthalmol
December 2024
Division of Ophthalmology (EB-S, AS, AA-A, AS-B, DW, SS, FC), Department of Surgery, University of Calgary, Calgary, Canada; Department of Biomedical Engineering (CN), University of Calgary, Calgary, Canada; Departments of Neurology (LBDL) and Ophthalmology (LBDL), University of Michigan, Ann Arbor, Michigan; and Department of Clinical Neurosciences (SS, FC), University of Calgary, Calgary, Canada.
Background: Optic neuritis (ON) is a complex clinical syndrome that has diverse etiologies and treatments based on its subtypes. Notably, ON associated with multiple sclerosis (MS ON) has a good prognosis for recovery irrespective of treatment, whereas ON associated with other conditions including neuromyelitis optica spectrum disorders or myelin oligodendrocyte glycoprotein antibody-associated disease is often associated with less favorable outcomes. Delay in treatment of these non-MS ON subtypes can lead to irreversible vision loss.
View Article and Find Full Text PDFCurr Opin Crit Care
January 2025
Department of Critical Care Medicine.
Purpose Of Review: Neuroprognostication after acute brain injury (ABI) is complex. In this review, we examine the threats to accurate neuroprognostication, discuss strategies to mitigate the self-fulfilling prophecy, and how to approach the indeterminate prognosis.
Recent Findings: The goal of neuroprognostication is to provide a timely and accurate prediction of a patient's neurologic outcome so treatment can proceed in accordance with a patient's values and preferences.
Physiol Res
December 2024
Institute of Physiology, Czech Academy of Sciences, 14220 Prague 4, Czech Republic.
The history of the Czech and Slovak experimental cardiology describes a completely unusual curve. The personality of J.E.
View Article and Find Full Text PDFJ Am Coll Surg
January 2025
Department of Surgery, McGovern Medical School, Houston, Texas.
Background: In 2012, TQIP guidelines for massive transfusion protocols (MTP) recommended delivery of blood product coolers within 15 minutes. Subsequent work found that every minute delay in cooler arrival was associated with a 5% increased risk of mortality. We sought to assess the impact and sustainability of quality improvement (QI) interventions on time to MTP cooler delivery and their association with trauma patient survival.
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