Sparse coding algorithms with continuous latent variables have been the subject of a large number of studies. However, discrete latent spaces for sparse coding have been largely ignored. In this work, we study sparse coding with latents described by discrete instead of continuous prior distributions. We consider the general case in which the latents (while being sparse) can take on any value of a finite set of possible values and in which we learn the prior probability of any value from data. This approach can be applied to any data generated by discrete causes, and it can be applied as an approximation of continuous causes. As the prior probabilities are learned, the approach then allows for estimating the prior shape without assuming specific functional forms. To efficiently train the parameters of our probabilistic generative model, we apply a truncated expectation-maximization approach (expectation truncation) that we modify to work with a general discrete prior. We evaluate the performance of the algorithm by applying it to a variety of tasks: (1) we use artificial data to verify that the algorithm can recover the generating parameters from a random initialization, (2) use image patches of natural images and discuss the role of the prior for the extraction of image components, (3) use extracellular recordings of neurons to present a novel method of analysis for spiking neurons that includes an intuitive discretization strategy, and (4) apply the algorithm on the task of encoding audio waveforms of human speech. The diverse set of numerical experiments presented in this letter suggests that discrete sparse coding algorithms can scale efficiently to work with realistic data sets and provide novel statistical quantities to describe the structure of the data.
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http://dx.doi.org/10.1162/neco_a_01015 | DOI Listing |
J Thorac Cardiovasc Surg
January 2025
Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas; Department of Cardiovascular Surgery, The Texas Heart Institute, Houston, Texas. Electronic address:
Objectives: Although socioeconomic status (SES) is believed to affect patient outcomes after coronary artery bypass grafting (CABG), readmission data are sparse. In a national cohort, we analyzed the influence of SES on readmission, resource utilization, and mortality after CABG.
Methods: We queried the Nationwide Readmissions Database to identify patients who underwent isolated CABG from January 2016 through December 2018.
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View Article and Find Full Text PDFbioRxiv
January 2025
Center for Theoretical Neuroscience, Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY.
Storing complex correlated memories is significantly more efficient when memories are recoded to obtain compressed representations. Previous work has shown that compression can be implemented in a simple neural circuit, which can be described as a sparse autoencoder. The activity of the encoding units in these models recapitulates the activity of hippocampal neurons recorded in multiple experiments.
View Article and Find Full Text PDFUltrasound Med Biol
January 2025
Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong; Biomedical Engineering Programme, The University of Hong Kong, Hong Kong. Electronic address:
Objective: Near-field (NF) clutter filters are critical for unveiling true myocardial structure and dynamics. Randomized singular value decomposition (rSVD) stands out for its proven computational efficiency and robustness. This study investigates the effect of rSVD-based NF clutter filtering on myocardial motion estimation.
View Article and Find Full Text PDFJ Clin Exp Dent
December 2024
DDS. Titular Professor. Universidad de Antioquia U de A, Medellín, Colombia. Biomedical Stomatology Research Group, Universidad de Antioquia U de A, Medellín, Colombia.
Background: The RTK-VEGF4 receptor family, which includes VEGFR-1, VEGFR-2, and VEGFR-3, plays a crucial role in tissue regeneration by promoting angiogenesis, the formation of new blood vessels, and recruiting stem cells and immune cells. Machine learning, particularly graph neural networks (GNNs), has shown high accuracy in predicting these interactions. This study aims to predict drug-gene interactions of the RTK-VEGF4 receptor family in periodontal regeneration using graph neural networks.
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