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Pain Management Services Can Be a Cost-Effective Option over Surgery for the Treatment of Chronic Pain.
Curr Pain Headache Rep
January 2025
Department of Anesthesiology, University of Wisconsin, Madison, WI, 53711, USA.
Purpose Of Commentary: The number of facilities and physicians that offer pain management services has grown significantly since the 1970s. Despite the rise in prevalence of individuals with chronic pain during that time, interventional pain physicians remain underutilized. One reason why this may be the case is a large number of patients are referred directly to surgical specialists prior to being seen by an interventional pain physician.
View Article and Find Full Text PDFAssembly and Quantification of Co-Cultures Combining Heterotrophic Yeast with Phototrophic Sugar-Secreting Cyanobacteria.
J Vis Exp
December 2024
Institute for Synthetic Microbiology, Heinrich Heine University Düsseldorf; Department of Biochemistry and Molecular Biology, Michigan State University.
With the increasing demand for sustainable biotechnologies, mixed consortia containing a phototrophic microbe and heterotrophic partner species are being explored as a method for solar-driven bioproduction. One approach involves the use of CO2-fixing cyanobacteria that secrete organic carbon to support the metabolism of a co-cultivated heterotroph, which in turn transforms the carbon into higher-value goods or services. In this protocol, a technical description to assist the experimentalist in the establishment of a co-culture combining a sucrose-secreting cyanobacterial strain with a fungal partner(s), as represented by model yeast species, is provided.
View Article and Find Full Text PDFAntibodies against the multifaceted cathepsin D protein open new avenues for TNBC immunotherapy.
J Immunother Cancer
January 2025
IRCM, INSERM U1194, University of Montpellier, ICM, Montpellier, France
Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype characterized by aggressive clinical behavior and poor prognosis. The immune landscape associated with TNBC often reveals high immunogenicity. Therefore, immunotherapy, which has demonstrated its efficacy in different cancer types, could be a promising strategy for TNBC, given the limited therapeutic options currently available besides conventional chemotherapy.
View Article and Find Full Text PDFBest Practices in Formative Feedback in Resident Evaluations: A Narrative Review.
J Surg Educ
January 2025
Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland. Electronic address:
Background: Formative feedback is essential for the optimal development of a physician. The narrative portion of the evaluation is uniquely poised to help guide the resident. However, the quality of the feedback may be highly variable, and evaluators may be hampered by both a lack of formal training as well as time pressures.
View Article and Find Full Text PDFTitle: Can ChatGPT 4.0 Reliably Answer Patient Frequently Asked Questions About Boxer's Fractures?
Hand Surg Rehabil
January 2025
Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York City, NY, United States.
Background: Patients are increasingly turning to the internet, and recently artificial intelligence engines (e.g., ChatGPT), for answers to common medical questions.
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