In neurons, correct targeting of receptors to the axon is critical for cell survival and circuit formation. In this issue of Developmental Cell, Yamashita et al. (2017) report that the ER-resident phosphatase PTP1B is required to prime TrkA for axonal transport.
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| http://dx.doi.org/10.1016/j.devcel.2017.09.002 | DOI Listing |
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