Introduction : application of evidence-based practice (EBP) by nurses is uneven and inconsistent. Background : characteristics related to head nurses and organizations influence their interventions to the detriment of EBP. Objectives : this integrative literature review informed by the knowledge-to-action (KTA) framework developed by Straus, Tetroe, and Graham (1) sought to identify the barriers and facilitators encountered by head nurses when implementing EBP among hospital staff nurses. It also sought to put in evidence interventions to promote lasting implementation of EBP. Method : an electronic search of the empirical literature was conducted on three databases. Of 532 articles found, 16 were retained and analysed. Results : various interventions could be delivered by head nurses and organizations centred on each steps of the KTA process proposed by Straus, Tetroe and Graham (1). Staff nurses would also benefit from interventions targeting communication, role modeling, and support delivered at all times. Conclusion : head nurses and organizations could foster EBP among staff nurses by delivering promising interventions that take account of the local context and of implementation barriers and facilitators.

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