Both Mg2+ and oligomycin are required for the establishment of a membrane potential and the uptake of Cl- in submitochondrial particles prepared from rat liver. The effect of oligomycin is considered to be due to blocking of H+ conduction through exposed F0 channels of the ATPase complex whereas Mg2+ may more directly affect the anion-conducting channel.
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| http://dx.doi.org/10.1016/0014-5793(88)80814-7 | DOI Listing |
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