Ethnopharmacological Relevance: Although Luehea divaricata Mart. (Malvaceae) is popularly used by the population of the Brazilian Pantanal for the treatment of different types of kidney diseases, no study has been carried out to prove this ethnobotanical indication.
Aim: To investigate the possible cardiorenal effects of an herbal preparation obtained from L. divaricata leaves.
Materials And Methods: First, to provide quality control standards, a detailed morphological and microchemical characterization of L. divaricata leaves was performed. Then, the purified aqueous extract was obtained from the leaves of this species (ESLD) and a thorough phytochemical characterization was performed. Subsequently, acute oral toxicity test was performed after single administration of different doses (5, 50, 300, 2000mg/kg) in male and female Wistar rats. Finally, the diuretic, hypotensive and antioxidant properties of ESLD (30, 100, 300mg/kg) were evaluated after acute and prolonged treatment and the role of angiotensin converting enzyme, aldosterone, vasopressin, and nitric oxide in these effects was investigated.
Results: Analyses performed by liquid chromatography-mass spectrometry showed that the main secondary metabolites present in ESLD were flavonol O-glycosides and flavone C-glycosides. Acute and prolonged treatment with ESLD was able to expressively increase urinary volume and electrolyte excretion. Mean blood pressure and systolic blood pressure were also significantly reduced after acute treatment. Moreover, treatment with ESLD was able to reduce thiobarbituric acid reactive species and increase serum nitrate levels.
Conclusion: The data obtained showed that ESLD has an important diuretic and hypotensive effect, which is probably dependent on the reduction of oxidative stress and increased bioavailability of nitric oxide.
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http://dx.doi.org/10.1016/j.jep.2017.09.020 | DOI Listing |
Zootaxa
July 2024
Programa de Pós-Graduação em Ecologia e Conservação da Biodiversidade; Instituto de Biociências; Universidade Federal de Mato Grosso; Av. Fernando Corrêa da Costa; 2367; 78060-900; Cuiabá; Mato Grosso; Brazil; Programa de Pós-Graduação em Zoologia; Instituto de Biociências; Universidade Federal de Mato Grosso; Brazil; Faculdade de Medicina Veterinária; Universidade Federal de Mato Grosso; Brazil.
We report data on morphological variation and behavior of the recently described watersnake Helicops boitata, previously known strictly from the holotype. Our data come from five new specimens fortuitously found in a private area near the type locality, in the Brazilian Pantanal wetlands. The expanded sample revealed polymorphism in at least two scalation features previously assumed as diagnostic of the species (i.
View Article and Find Full Text PDFAn Acad Bras Cienc
December 2024
Universidade Federal de Lavras, Faculdade de Zootecnia e Medicina Veterinária, Trevo Professor Edmir Sá Santos, 37203-202 Lavras, MG, Brazil.
Leaf litter is an important component related to nutrient cycling and conservation of soil biodiversity. In this context, the objective of our study was to investigate the relationship between soil and leaf litter in different forest communities in sub-regions of the Pantanal (Nhecolândia and Abobral/Miranda). To this end, we collected soil and leaf litter samples from 152 sample plots divided in physiognomies regionally called as Cordilheira, Capão, Murundu, Corixo and Cambará/Canjiqueira forest.
View Article and Find Full Text PDFMicroorganisms
November 2024
Vector-Borne Bioagents Laboratory (VBBL), Faculdade de Ciências Agrárias e Veterinárias (FCAV), Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), Jaboticabal 14884-900, São Paulo, Brazil.
Sci Total Environ
October 2023
Embrapa Pantanal, Corumbá, MS, Brazil. Electronic address:
The resurgent navigation project known as the Hidrovia Paraguay-Paraná threatens the integrity of the Pantanal, the world's largest wetland, which is considered a biome of its own. Intensive barge navigation is intended to transport crops (soybean, sugar, corn) and cement, iron and manganese from areas of production in Brazil, Paraguay and Bolivia to the oceanic ports of the Plata River. This short communication assembles the information available on the potential impacts of the planned deepening of the natural channel of the Paraguay River in its ~700 km-long upper section.
View Article and Find Full Text PDFJ Helminthol
October 2024
Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, Pampulha, CEP 31270-901, Belo Horizonte, MG, Brasil.
(Baylis, 1927) is a widespread nematode in South America that infects different species of anurans from different families. Although the morphology of this species shows intraspecific variations and is well studied, does not have genetic characterisation. Therefore, the present study aimed to provide the first genetic characterisation of this parasite, based on 18S and 28S rDNA sequences, as well as to evaluate its phylogenetic position in the family Cosmocercidae.
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