Vitiligo is a disorder characterized by the development of depigmented macules and patches secondary to melanocyte destruction. Several treatment options are available, including medical, light-based, and surgical therapies, that are often used in combination to achieve maximal repigmentation. Vitiligo surgery is an effective yet underperformed treatment, mainly because of lack of awareness and availability. The purpose of this article is to review one method of vitiligo surgery, the melanocyte-keratinocyte transplantation procedure, and discuss its utility in treating vitiligo.
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http://dx.doi.org/10.1016/j.jisp.2017.01.001 | DOI Listing |
Medicina (Kaunas)
January 2025
Unit of Dermatology and Cosmetology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
: Janus kinase inhibitors (JAKi) have significantly advanced the treatment of various dermatological conditions by modulating the JAK-STAT signalling pathway. While these inhibitors have proven effective, they also pose challenges due to associated increase in serum lipid levels and relative potential cardiovascular risks. This perspective work aims to discuss the implications of these lipid alterations proposing management strategies for patients with dermatological disorders under JAKi treatments.
View Article and Find Full Text PDFIndian Dermatol Online J
December 2024
Department of Dermatology, Maharashtra Medical Foundation's Joshi Hospital, Pune, Maharashtra, India.
J Cosmet Dermatol
January 2025
Department of Dermatology, University of Athens School of Medicine, Andreas Sygros Hospital, Athens, Greece.
Objective: NCTF135HA, a versatile polyrevitalizing solution, is a potent agent for enhancing skin quality, radiance, moisture, vitality, and diminishing fine wrinkles caused by aging factors. Data demonstrate a divergence in its application from skin quality enhancement to treatment of vitiligo lesions. To know more precisely about the protocol of use among providers, alone or in combination with other procedures, we performed an international survey.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
December 2024
Dr. Grimes is the Founder and Director at the Vitiligo & Pigmentation Institute of Southern California in Los Angeles, California; Clinical Professor of Dermatology at the University of California, Los Angeles. Current President of the Global Vitiligo Foundation.
This article is based on a roundtable discussion in which three panelists review clinically relevant insights about vitiligo and discuss two cases that illustrate the multiple challenges faced by both patients and clinicians in managing this complex disease. The first is a 32-year-old White female patient with Fitzpatrick Skin Type III/IV with extensive depigmentation in the trunk area. The patient achieved 90-percent repigmentation with a combination therapy approach.
View Article and Find Full Text PDFArch Dermatol Res
January 2025
Dermatology and Venereology Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Both the surgical non-cultured melanocyte-keratinocyte transplant procedure (MKTP) and intradermal injection of 5-Fluorouracil (5-FU) are effective in the treatment of vitiligo. Intrablisters injection of MKTP was done in one study with better results than MKTP application after ablative CO2 laser of the reciepient area. However, intrablister injection of 5-FU was not done before.
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