Association of heart dose and overall survival was investigated in a cohort including 469 locally-advanced NSCLC patients receiving daily low-dose hypofractionated chemo-radiotherapy. Significant associations were found over a range of dose parameters. Multivariate analysis showed significant associations of heart_V:HR=1.007% (95% CI:1.002-1.013; p=0.006), age:HR=1.026year (1.011-1.042; p=0.001) and GTV volume:HR=1.001cc (1.000-1.002; p=0.006) with overall survival.
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| http://dx.doi.org/10.1016/j.radonc.2017.09.004 | DOI Listing |
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