The evolving landscape of new diagnostic tests for invasive aspergillosis in hematology patients: strengths and weaknesses.

Dieter Buchheidt Mark Reinwald Martin Hoenigl Wolf-Karsten Hofmann Birgit Spiess Tobias Boch

Curr Opin Infect Dis

aDepartment of Internal Medicine - Hematology and Oncology, Mannheim University Hospital, Heidelberg University, Heidelberg bSecond Department of Internal Medicine, Brandenburg University Hospital, Brandenburg, Germany cDivision of Infectious Diseases, Department of Medicine, University of California -San Diego, San Diego, California, USA dSection of Infectious Diseases and Tropical Medicine, Department of Internal Medicine eDivision of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

Published: December 2017

Purpose Of Review: The diagnosis of invasive aspergillosis in hematologic patients is a complex composite of clinical preconditions and features, imaging findings, biomarker combinations from appropriate clinical samples and microbiological and/or histological findings.

Recent Findings: Recent developments in the evolving landscape of diagnostic tests for invasive aspergillosis in adult hematology patients are highlighted.

Summary: Novel approaches and tools are currently under development. Focusing optimized diagnostic performance, in particular the combination of biomarkers from appropriate clinical samples, improved diagnostic performance distinctly.

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http://dx.doi.org/10.1097/QCO.0000000000000408	DOI Listing

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