Within this study, a new system which measures and analyzes electrical skin impedance in 48 channels within a 2.5 × 3.5 cm matrix is used in rehabilitation medicine for the first time. Electrodermal activity was measured in 20 patients before and after two different non-surgical treatments of a completely ruptured anterior cruciate ligament. The first treatment, RegentK, was developed by Mohamed Khalifa, the second is a standard physiotherapy. The patients in the two groups were age-matched, and all demographic data showed no significant differences. It was interesting that electrodermal activity was significantly decreased only after RegentK. We conclude that not only local effects of pressure application are responsible for these results, rather as yet unknown neurovegetative mechanisms have to be taken into consideration.
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http://dx.doi.org/10.3390/medicines1010022 | DOI Listing |
Alzheimers Dement
December 2024
University of Michigan Medical School, Ann Arbor, MI, USA.
Background: Cognitive changes affecting performance are subtle in early stages of Alzheimer's Disease (AD) and may emerge only with more complex tasks. Driving is a highly challenging instrumental activity of daily living, requiring higher order integration of cognitive skills. For example, driving on freeway entrance ramps requires heightened cognitive engagement such as rapid responses to fast-emerging traffic and sudden speed changes, combining sensory processing and manipulative actions.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Ontario Shores Centre for Mental Health Sciences, Whitby, ON, Canada.
Background: Previous literature has highlighted that excessive alcohol use (EAU) is directly linked with permanent neurological damage. Studies have also highlighted gradual improvements in heart rate variability (HRV) after cessation of alcohol use. Moreover, chronic alcohol consumption has also been correlated with reduced HRV and an increase in skin conductance (SC) among healthy adults, leading to a combined decline in cognitive performance.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Michigan Medical School, Ann Arbor, MI, USA.
Background: Identifying markers for increased risk of cognitive change and early Alzheimer's disease (AD) is key to enhancing the effectiveness of treatments. Changes in instrumental activities of daily living, including the complex task of driving, may serve as potential markers to identify older adults at risk of cognitive decline. This study evaluates driving behaviors and associated physiological signals in older adults with and without elevated brain amyloid burden.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Michigan Medical School, Ann Arbor, MI, USA.
Background: Early symptoms of Alzheimer's disease (AD) may include subtle performance changes in complex tasks, such as driving, which could be potential markers for identifying those at risk of cognitive decline. In this study, categorical driving behaviors and events as well as related physiological changes were compared in older adults with and without elevated brain amyloid.
Method: Video and physiological data collected from 21 amyloid positive and 21 amyloid negative participants over the age of 65 (range 65-85), who participated in the University of Michigan's Driving and Physiological Responses study were analyzed.
Physiol Meas
January 2025
Emory University School of Medicine, 101 Woodruff Circle, Atlanta, Atlanta, Georgia, 30322, UNITED STATES.
Objective: This study aims to evaluate the efficacy of wearable physiology and movement sensors in identifying a spectrum of challenging behaviors, including self-injurious behavior (SIB), in children and teenagers with autism spectrum disorder (ASD) in real-world settings.
Approach: We utilized a long-short-term memory (LSTM) network with features derived using the wavelet scatter transform to analyze physiological biosignals, including electrodermal activity and skin temperature, alongside three-dimensional movement data captured via accelerometers. The study was conducted in naturalistic environments, focusing on participants' daily activities.
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