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Adherence to positive airway pressure therapy in patients with Down syndrome: assessing cloud based monitoring data.
J Clin Sleep Med
December 2024
Department of Medicine, Univ of California at San Diego, La Jolla, CA.
Study Objectives: Obstructive sleep apnea (OSA) is common in Down syndrome (DS) with many patients prescribed positive airway pressure (PAP) therapy. This study evaluates PAP adherence and identifies factors influencing adherence.
Methods: Retrospective analysis of electronic health records and cloud-based PAP therapy data from DS patients at Rady Children's Hospital, San Diego, CA.
How does gut microbiota affect the vaginitis axis? The mediating role of plasma metabolites.
Microbiol Spectr
December 2024
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Vaginitis is the most common problem afflicting women of childbearing age. However, the underlying etiological factors remain poorly understood, leading to recurrent vaginitis and constraining clinical management. Here, we explored whether the gut microbiota influences the risk of vaginitis by performing a two-sample Mendelian randomization analysis using the largest genome-wide association studies to date.
View Article and Find Full Text PDFAgenesis of maxillary lateral incisors: Bone formation by orthodontic tooth movement and long-term stability of the edentulous alveolar ridge at 12-15 years after treatment.
Am J Orthod Dentofacial Orthop
January 2025
Department of Orthodontics, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic; Department of Dentistry, First Faculty of Medicine, Charles University and the General University Hospital, Prague, Czech Republic. Electronic address:
Introduction: The primary aim of this study was to assess the amount and long-term stability of orthodontically created bone in patients with agenesis of maxillary lateral incisors after canine distalization. The secondary aim was to explore the impact of patient age on the process of alveolar bone resorption.
Methods: A group of patients with agenesis of the maxillary permanent lateral incisor was examined at 4 time points: the beginning of orthodontic treatment (T1, n = 80), the end of treatment (T2, n = 80), 2-5 years after treatment (T3, n = 79), and 12-15 years after treatment (T4, n = 32).
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with significant comorbidities, including cardiovascular and respiratory complications, leading to increased hospitalization rates in Intensive Care Units (ICUs) and Cardiac Intensive Care Units (CICUs). This study examines factors related to ICU/CICU admissions among Polish RA patients from 2011 to 2021.
Objectives: The study aims to analyze trends in ICU/CICU admissions, identify key factors influencing outcomes, and assess the impact of comorbidities on RA patient ICU/CICU mortality in critical care settings.
A novel robust network construction and analysis workflow for mining infant microbiota relationships.
mSystems
December 2024
Laboratory of Microbiology, Immunology, and Metabolism, Diprobio (Shanghai) Co., Limited, Shanghai, China.
Unlabelled: The gut microbiota plays a crucial role in infant health, with its development during the first 1,000 days influencing health outcomes. Understanding the relationships within the microbiota is essential to linking its maturation process to these outcomes. Several network-based methods have been developed to analyze the developing patterns of infant microbiota, but evaluating the reliability and effectiveness of these approaches remains a challenge.
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