IFN-λ 'guts' neutrophil-mediated inflammation.

Nat Immunol

Department of Immunology, University of Washington, Seattle, Washington, USA.

Published: September 2017

Interferon-λ (IFN-λ) curbs neutrophil-mediated intestinal inflammation by diminishing the production of reactive oxygen species and subsequent oxidative stress. This regulatory process is unique to IFN-λ and is independent of interferon-induced transcription and translation programs.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661971PMC
http://dx.doi.org/10.1038/ni.3834DOI Listing

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