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Deer antlers exhibit rapid growth during the velvet phase. As a critical endogenous growth factor in animals, midkine (MDK) is likely closely associated with the growth of antlers. However, the spatio-temporal expression pattern of MDK during the velvet phase was unclear.

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Here, we present a previously undescribed approach to modify N-terminal sequences of recombinant proteins to increase their production yield in Escherichia coli. Prior research has demonstrated that the nucleotides immediately following the start codon can significantly influence protein expression. However, the impact of these sequences is construct-specific and is not universally applicable to all proteins.

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Maize ( L.) is a major food and feed crop and an important raw material for energy, chemicals, and livestock. The NF-Y family of transcription factors in maize plays a crucial role in the regulation of plant development and response to environmental stress.

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Decoding the structure of isopentenyl Diphosphate Delta-Isomerase protein from Vahl.

J Biomol Struct Dyn

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Department of Biochemistry & Forensic Science, University School of Sciences, Gujarat University, Ahmedabad, Gujarat, India.

Senna ( Vahl.) is an important medicinal plant used in traditional and modern systems medicine to manage constipation. While various treatment strategies exist, there is growing interest in utilizing traditional herbal medicines like Indian Senna as a natural alternative.

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The predominant role of FliC contributes to the flagella-related pathogenicity of ST34 S. Typhimurium monophasic variant.

Vet Res

December 2024

Jiangsu Key Lab of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.

Article Synopsis
  • Over the last two decades, the monophasic variant of Salmonella enterica serovar Typhimurium, particularly the European ST34 clone, has rapidly increased in prevalence worldwide.
  • The distinct difference in ST34 S. Typhimurium is the replacement of the fljB gene, which encodes for a second-phase flagellin, with multidrug resistance cassettes, raising questions about its pathogenicity.
  • Research shows that while the absence of fljB doesn’t significantly impact various virulence factors, the deletion of the fliC gene, which encodes for the first-phase flagellin, does lead to a major reduction in these factors, indicating that fliC is crucial for the bacterium’s mot
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