In Japan and North America, different dosimetry protocols have been implemented to determine the absorbed dose to water: JSMP Standard Dosimetry 12 and AAPM TG-51 addendum. In this study, Japanese and Canadian reference dosimetries for high energy photon beams were compared theoretically, and then they were verified experimentally. We estimated the theoretical differences of the ion recombination correction factors, the leakage correction factors, the radial dose distribution correction factors, the calibration factors, the beam quality correction factors and the absorbed dose to water. When an influence of the radial dose distribution is negligible, the ratios of Canadian to Japanese absorbed dose in reference dosimetries ranged from 0.995 to 1.007 for all the reference-class-Farmer-type ionization chambers. This discrepancy was mainly caused by the wall correction factor included in the beam quality correction factor. Subsequently, to verify the theoretical approaches, we calibrated the same ionization chamber in Co gamma ray of Japanese primary and secondary standard dosimetry laboratories (PSDL and SSDL) and measured the absorbed dose of a clinical linear accelerator. It followed that the ratios of Canadian to Japanese absorbed dose in reference dosimetries increased up to 1.015 for PTW 30013 reference-class-Farmer-type ionization chamber. This increase was mainly caused by a discrepancy in the calibration factors (N) observed between Japanese PSDL and SSDL. In conclusion, in order to improve the international consistency of the absorbed dose to water determined by JSMP Standard Dosimetry 12, we should reevaluate the accuracy of the wall correction factors and implement a periodic comparative test of the N between Japanese PSDL and SSDL.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.11323/jjmp.37.1_25 | DOI Listing |
Asia Ocean J Nucl Med Biol
January 2025
Nuclear Fuel Cycle Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.
Objectives: Liver malignancies are among the most prevalent causes of cancer-related deaths worldwide. Intra-arterial administration of particulates labeled with beta-emitting radionuclides is one of the non-surgical promising modalities for the treatment of liver cancer.
Methods: In this work, the radiation absorbed dose of Ho-hydroxyapatite (Ho-HA) radiopharmaceutical was estimated for adult men based on biodistribution data in normal Wistar rats.
Eur J Nucl Med Mol Imaging
January 2025
Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, 3015 GD, The Netherlands.
J Ethnopharmacol
December 2024
Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan, 430065, China; Key Laboratory of Chinese Medicine Resource and Compound Prescription, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, China. Electronic address:
Ethnopharmacological Relevance: Cognitive dysfunction is a common complication of chronic insomnia. Liuwei Anshen Capsules (LAC), a traditional Chinese patent medicine clinically prescribed for insomnia, has been proved to possess good efficacy in reducing insomnia complications including dementia and anxiety in clinic. However, the active substances in LAC and their mechanisms in treating cognitive deficit associated with sleep disorders remain unclear.
View Article and Find Full Text PDFSci Rep
December 2024
Sustainability Solutions Research Lab, Faculty of Engineering, University of Pannonia, Egyetem Str. 10, Veszprém, 8200, Hungary.
Ensuring everyone enjoys healthy lifestyles and well-being at all ages, Progress has been made in increasing access to clean water and sanitation facilities and reducing the spread of epidemics and diseases. The synthesis of nano-particles (NPs) by using microalgae is a new nanobiotechnology due to the use of the biomolecular (corona) of microalgae as a capping and reducing agent for NP creation. This investigation explores the capacity of a distinct indigenous microalgal strain to synthesize silver nano-particles (AgNPs), as well as its effectiveness against multi-drug resistant (MDR) bacteria and its ability to degrade Azo dye (Methyl Red) in wastewater.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
December 2024
Department of Biotechnology and Molecular Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Background: One key feature that distinguishes cancerous cell populations from their normal counterparts is a heightened tendency towards uncontrolled growth and invasive activity. Therapeutic techniques like radiotherapy can impact the viability and invasive behavior of cancer cells by modifying the structure of DNA and inducing programmed cell death.
Methods: This research is an experimental study and involved a comprehensive investigation into the effects of 6MV X-ray radiotherapy on various absorbed doses (ranging from 4 to 10 Gy by steps 2Gy) on toxicity, migration, and colony formation in C6 glioblastoma cellular cultures.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!