Leiomyosarcoma is a rare form of soft tissue neoplasm, with only 1% to 5% occurring in the head and neck region. Current recommended treatment suggests surgical excision with a wide lateral margin, but no definite guidelines regarding excisional margin have been established yet. Recently, complete excision with a narrow surgical margin has been recommended, and the authors present a case of cutaneous leiomyosarcoma on the face that was successfully managed by complete removal with a narrow excisional margin. A 74-year-old woman presented with a 3 cm sized, rapidly growing cutaneous mass on her right preauricular area. Preoperative biopsy of the skin lesion suggested a cutaneous leiomyosarcoma. The authors performed complete surgical excision with a 1 cm lateral margin, and the resulting skin defect was repaired with bilateral V-Y advancement local flaps. Histopathology and immunohistochemistry evaluation confirmed a moderately differentiated cutaneous leiomyosarcoma, with negative margin involvement. The patient refused of any additional treatment, but showed no locoregional recurrence during the 1.5 years of postoperative follow-up period. With a regular postoperative follow-up, cutaneous leiomyosarcomas may be successfully treated with a narrow surgical margin.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556711 | PMC |
http://dx.doi.org/10.7181/acfs.2014.15.1.36 | DOI Listing |
Arch Dermatol Res
December 2024
Department of Dermatology, University of Nebraska Medical Center, Omaha, NE, USA.
Arch Dermatol Res
December 2024
Department of Dermatology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
J Am Acad Dermatol
November 2024
Department of Dermatology, University of California Davis Health, Sacramento, California; Touro University California College of Osteopathic Medicine, Vallejo, California; University of Florida College of Medicine, Maples Center for Forensic Medicine, Gainesville, Florida. Electronic address:
J Am Acad Dermatol
November 2024
American Medical Program, Tel Aviv University, Tel Aviv, Israel.
J Am Acad Dermatol
October 2024
Department of Plastic Surgery and Burns Treatment, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.
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