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http://dx.doi.org/10.1097/NNA.0000000000000527 | DOI Listing |
Am J Chin Med
January 2025
School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China.
Palmatine (PAL) and berberine are both classified as protoberberine alkaloids, derived from several traditional Chinese herbs such as Franch. and Schneid. These compounds are extensively used in treating dysentery and colitis.
View Article and Find Full Text PDFBr J Radiol
January 2025
2nd Department of Radiology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Greece.
In a rapidly evolving healthcare environment, artificial intelligence (AI) is transforming diagnostic techniques and personalised medicine. This is also seen in osseous biopsies. AI applications in radiomics, histopathology, predictive modelling, biopsy navigation, and interdisciplinary communication are reshaping how bone biopsies are conducted and interpreted.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Department of Urology, Beilun People's Hospital, Ningbo, Zhejiang, China.
Renal ischemia-reperfusion (IR) induces tissue hypoxia, resulting in disrupted energy metabolism and heightened oxidative stress. These factors contribute to tubular cell damage, which is a leading cause of acute kidney injury (AKI) and can progress to chronic kidney disease (CKD). The excessive generation of reactive oxygen species (ROS) plays a crucial role in the pathogenesis of AKI.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Yunnan Key Laboratory of Cell Metabolism and Diseases, Yunnan University, Kunming, China.
Single-cell protein analysis has emerged as a powerful tool for understanding cellular heterogeneity and deciphering the complex mechanisms governing cellular function and fate. This review provides a comprehensive examination of the latest methodologies, including sophisticated cell isolation techniques (Fluorescence-Activated Cell Sorting (FACS), Magnetic-Activated Cell Sorting (MACS), Laser Capture Microdissection (LCM), manual cell picking, and microfluidics) and advanced approaches for protein profiling and protein-protein interaction analysis. The unique strengths, limitations, and opportunities of each method are discussed, along with their contributions to unraveling gene regulatory networks, cellular states, and disease mechanisms.
View Article and Find Full Text PDFCureus
January 2025
Emergency Medicine Department, Maidstone and Tunbridge Wells NHS Trust, Maidstone, GBR.
Visual impairment and eye disease remain a significant burden, highlighting the need for further support regarding eye care services. Artificial intelligence (AI) and its rapid advancements are providing an avenue for transforming healthcare. As a result, this provides a potential avenue to address the growing challenges with eye health and could assist in settings such as eye casualty departments.
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