Spinal anesthesia complicated by meningitis is rare. The diagnosis is difficult and the clinical signs are unspecific. There is a subgroup called aseptic meningitis of a different mechanism (hypersensitive reaction and irritation of the meninges), which must be identified for appropriate care. We report the case of aseptic meningitis resulting from bupivacaine use complicating spinal anesthesia. She is 31 years old and was admitted to the intensive care unit for meningitis following a Caesarean delivery. 10 hours after the procedure, she was found to have severe headache, neck stiffness and was found restless. She lost consciousness; she was treated by attending physicians. A CT scan have been performed and was found normal. 24 hours after intubation, the patient woke up. The clinical and biological valuations were normal, allowing for the elimination of the other causes of meningitis.
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http://dx.doi.org/10.11604/pamj.2017.27.192.9327 | DOI Listing |
Interv Pain Med
March 2025
Department of Anesthesiology, Massachusetts General Hospital, Boston, MA, USA.
Cureus
December 2024
Internal Medicine, Merit Health Wesley, Hattiesburg, USA.
This case report highlights the complex clinical presentation of a 43-year-old male with a history of renal transplantation, hypertension, and diabetes mellitus, who developed viral meningitis with probable metabolic encephalopathy. The multidisciplinary approach involved infectious disease specialists, transplant nephrologists, and neurologists. This case provides unique learning points such as highlighting the complexities of diagnosing and managing viral meningitis in an immunocompromised post-transplant patient, emphasizing the importance of a multidisciplinary approach, innovative medication delivery, and awareness for complications such as metabolic encephalopathy and persistent fevers.
View Article and Find Full Text PDFFront Immunol
January 2025
Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
The non-polio Enteroviruses (NPEVs), consist of enteroviruses, coxsackieviruses, echoviruses, and rhinoviruses, are causative agents for a wide variety of diseases, ranging from common cold to encephalitis and acute flaccid paralysis (AFP). In recent years, several NPEVs have become serious public health threats, include EV-A71, which has caused epidemics of hand-foot-and-mouth disease (HMFD) in Southeast Asia, and EV-D68, which caused outbreaks of severe respiratory disease in children worldwide. Infections with these viruses are associated with neurological diseases like aseptic meningitis and AFP.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
Department of Pediatrics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Background: Bacterial meningitis (BM) is a life-threatening central nervous system infection with potential for severe neurological sequelae. High mobility group box 1 (HMGB1) is known as a late inflammatory mediator associated with lethal pathology. This study aims to investigate the serial cerebrospinal fluid (CSF) concentrations of HMGB1 in children with BM and its relationship to neurological prognosis.
View Article and Find Full Text PDFJ Community Hosp Intern Med Perspect
November 2024
MedStar Health Internal Medicine Residency Program, USA.
Herpes simplex virus (HSV) is well known to cause Central Nervous System (CNS) infections, ranging from more common HSV-2 viral meningitis to the more rare and severe HSV-1 encephalitis. Here we present an atypical case of aseptic meningitis due to HSV-1. Intriguingly, despite the potential severity of HSV-1 infections, the patient had an uncomplicated course with only mild symptoms that resolved with conservative management alone.
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