Reversal of tenofovir induced nephrotoxicity: case reports of two patients.

Pan Afr Med J

Department of Pharmacology and Toxicology, Moi University School of Medicine, P.O. Box 4606, Eldoret, Kenya.

Published: September 2017

The use of the antiretroviral drug tenofovir has been associated with nephrotoxicity. However, the overall impact of this adverse effect has not comprehensively evaluated. Some researchers have reported that it is quite severe to warrant monitoring for renal toxicity, while others have concluded that the magnitude may not be that significant. We report two clinical cases seen in our renal clinic with high creatinine levels suggestive of nephrotoxicity who reverted back to normality upon withdrawal of tenofovir.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567942PMC
http://dx.doi.org/10.11604/pamj.2017.27.126.10033DOI Listing

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