The purpose of this experiment was to investigate whether low-intensity pulsed ultrasound (LIPUS) irradiation can inhibit dentoalveolar ankylosis in transplanted rat teeth. LIPUS irradiation (the pulsed ultrasound signal had a frequency of 3.0 MHz, a spatial average intensity of 30 mW/cm, and a pulse ratio of 1:4) was performed on the face over the re-planted teeth of rats for 4 weeks. After the rats were euthanized, we measured mobility (Periotest value [PTV]) of the transplanted and control teeth using a Periotest. Finally, we performed histological evaluation to detect ankylosis. PTVs tended to be significantly lower for re-planted teeth than for control teeth. Histological evaluation revealed that the roots of all re-planted teeth were coalescent with alveolar bone. Furthermore, no ankylosis was observed in three-fifths of the re-planted teeth following LIPUS irradiation. These results indicate the potential efficacy of LIPUS to inhibit dentoalveolar ankylosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2334/josnusd.16-0551 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ultrasound-assisted and Efficient Multicomponent Synthesis of 4H-Pyran Derivatives catalyzed by LiOH.H2O in Water.
Curr Org Synth
January 2025
Laboratoire de Chimie Organique (LR17ES08), Faculté des Sciences de Sfax, University of Sfax, Route de Soukra Km 3.5, BP 1171, 3000, Sfax, Tunisia.
Aim And Objective: It is well established that 4H-pyran derivatives hold a significant position in synthetic organic chemistry due to their diverse biological and pharmacological properties. This work aims to introduce a novel synthetic pathway for highly functionalized 4H-pyran derivatives, achieved through a 1,4-Michael addition followed by a cascade cyclization. This reaction is catalyzed by LiOH·H2O under ultrasonic irradiation in water, offering an efficient and environmentally friendly approach.
View Article and Find Full Text PDFLow-Intensity Pulsed Ultrasound Delays the Onset of Osteoporosis and Dyslipidemia in Mice With Premature Ovarian Insufficiency.
J Ultrasound Med
January 2025
State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, China.
Objectives: The pathogenesis of premature ovarian insufficiency (POI) not only affects the ovarian structure and function but also gives rise to complications such as osteoporosis and dyslipidemia. Although low-intensity pulsed ultrasound (LIPUS) has been proven effective in treating POI, its impact on the associated complications remains unexplored. Therefore, this study aims to investigate the effects of LIPUS irradiation on osteoporosis and dyslipidemia in a mouse model of POI.
View Article and Find Full Text PDFCochineal ( Costa) Pigment Extraction Assisted by Ultrasound and Microwave Techniques.
Molecules
November 2024
Centro de Investigación en Biotecnología Aplicada, Instituto Politécnico Nacional, Ex-Hacienda San Juan Molino Carretera Estatal Tecuexcomac-Tepetitla Km. 1.5, Tepetitla de Lardizábal 90700, Tlaxcala, Mexico.
Carminic acid is a natural pigment typically found in several insect taxa, including specific insects such as "grana cochinilla fina" in Mexico ( Costa). Commercially, it is also referred to as carmine, which is a more concentrated solution presenting as at least 50% carminic acid. To date, this dye has been used in the pharmaceutical, food and cosmetic industries.
View Article and Find Full Text PDFA supramolecular assembly strategy for the treatment of rheumatoid arthritis with ultrasound-augmented inflammatory microenvironment reprograming.
Biomaterials
May 2025
Strait Institute of Flexible Electronics (SIFE, Future Technologies), College of Photonic and Electronic Engineering, Fujian Key Laboratory of Flexible Electronics and Strait Laboratory of Flexible Electronics (SLoFE), Fujian Normal University, Fuzhou, 350117, China. Electronic address:
As regulators and promotors of joint erosion, pro-inflammatory M1-like macrophages play pivotal roles in the pathogenesis of rheumatoid arthritis (RA). Here, we develop a supramolecular self-assembly (PCSN@MTX) of molybdenum (Mo) based polyoxometalate (POM), β-cyclodextrin (β-CD), and methotrexate (MTX), in which the MTX is loaded by host-guest interaction. PCSN@MTX shows inhibition of synovial M1-like macrophages polarization to alleviate RA.
View Article and Find Full Text PDFTRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in the mammalian brain.
Proc Natl Acad Sci U S A
December 2024
Advanced Neuroimaging Center, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Ultrasound neuromodulation has become an innovative technology that enables noninvasive intervention in mammalian brain circuits with high spatiotemporal precision. Despite the expanding utility of ultrasound neuromodulation in the neuroscience research field and clinical applications, the molecular and cellular mechanisms by which ultrasound impacts neural activity in the brain are still largely unknown. Here, we report that transient receptor potential canonical 6 (TRPC6), a mechanosensitive nonselective cation channel, is essential for ultrasound neuromodulation of mammalian neurons in vitro and in vivo.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!