https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=28904036&retmode=xml&tool=Litmetric&email=readroberts32@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09 289040362018061520211204
1715-52586392017SepCanadian family physician Medecin de famille canadienCan Fam PhysicianSacubitril-valsartan: novel therapy for heart failure.697697SehnEvanEDoctor of Pharmacy student at the University of Alberta in Edmonton.McDonaldTerrenceTAssistant Clinical Professor and Researcher in the Department of Family Medicine at the University of Calgary in Alberta.LindbladAdrienne JAJKnowledge Translation and Evidence Coordinator with the Alberta College of Family Physicians in Edmonton.engJournal Article
CanadaCan Fam Physician01203000008-350X0Aminobutyrates0Angiotensin Receptor Antagonists0Biphenyl Compounds0Drug Combinations0Tetrazoles114471-18-0Natriuretic Peptide, Brain80M03YXJ7IValsartanWB8FT61183sacubitril and valsartan sodium hydrate drug combinationIMAminobutyratesadverse effectstherapeutic useAngiotensin Receptor Antagonistsadverse effectstherapeutic useBiphenyl CompoundsDrug CombinationsHeart Failureblooddrug therapyHumansNatriuretic Peptide, BrainbloodTetrazolesadverse effectstherapeutic useValsartan
201791560201791560201861660201791ppublish28904036PMC559701563/9/697McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371(11):993–1004.25176015Latour-Pérez J, Coves-Orts FJ, Abad-Terrado C, Abraira V, Zamora J. Accuracy of B-type natriuretic peptide levels in the diagnosis of left ventricular dysfunction and heart failure: a systematic review. Eur J Heart Fail. 2006;8(4):390–9.16305826Lindblad AJ, Allan GM. Aldosterone antagonists in systolic heart failure. Can Fam Physician. 2014;60:e104. Available from: www.cfp.ca/content/cfp/60/2/e104.full.pdf. Accessed 2017 Jul 28.PMC392257724522687Moe GW, Ezekowitz JA, O’Meara E, Lepage S, Howlett JG, Fremes S, et al. The 2014 Canadian Cardiovascular Society heart failure management guidelines focus update: anemia, biomarkers, and recent therapeutic trial implications. Can J Cardiol. 2015;31(1):3–16. Erratum in: Can J Cardiol 2016;32(3):394.25532421Howlett JG, Chan M, Ezekowitz JA, Harkness K, Heckman GA, Kouz S, et al. The Canadian Cardiovascular Society heart failure companion: bridging guidelines to your practice. Can J Cardiol. 2016;32(3):296–310.26391749Entresto [product monograph]. Dorval, QC: Novartis Pharmaceuticals Canada Inc; 2016.Vardeny O, Claggett B, Packer M, Zile MR, Rouleau J, Swedberg K, et al. Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial. Eur J Heart Fail. 2016;18(10):1228–34.PMC509578427283779Canadian Agency for Drugs and Technologies in Health. CADTH Canadian Drug Expert Committee final recommendation: sacubitril/valsartan. Ottawa, ON: Canadian Agency for Drugs and Technologies in Health; 2016.Wang TD, Tan RS, Lee HY, Ihm SH, Rhee MY, Tomlinson B, et al. Effects of sacubitril/valsartan (LCZ696) on natriuresis, diuresis, blood pressures, and NT-proBNP in salt-sensitive hypertension. Hypertension. 2017;69(1):32–41.27849566