AI Article Synopsis
- Bird fancier's lung (BFL) is a disease linked to inhaling proteins from bird droppings, with past assumptions about harmful microorganisms also playing a role.
- Our study involved testing 15 BFL patients and 18 asymptomatic controls to assess antibody responses to both droppings and microorganisms.
- Results showed that most BFL patients had negative serological reactions to the microorganisms, suggesting that using a total extract from bird droppings is more effective for diagnosing the disease than relying on standard antigen panels.
Article Abstract
Bird fancier's lung (BFL) is a pulmonary disease caused by inhalation of avian proteins. The involvement of the microorganisms of droppings has been assumed in the past and this idea still persists today. Our study aimed to compare by immunoprecipitation assay the detection of antibodies against both droppings and microorganisms in the sera of patients (n=15) and asymptomatic exposed controls (n=18). We found that 14/15 BFL patients had negative serological results for isolated microorganisms of the droppings, only one positive against Enterobacter sakasakii. Serological arguments were in accordance with diagnosis in 87 % of cases by testing à la carte antigens from each bird dropping versus 20 % using the standard antigenic panel. Otherwise, the microorganisms antigens issued from dropping flora were negative in 93 % of cases. Consequently, it's preferable to use the total extract from the patient's bird droppings to establish the serodiagnosis of the disease.
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| http://dx.doi.org/10.1099/jmm.0.000586 | DOI Listing |
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