Background: Understanding of the pathogenesis of pain in the lumbopelvic region remains a challenge. It is suggested that lumbopelvic pain is related to decreased contraction of the transverse abdominal muscles (TrA).
Objective: To investigate how pain provoked by a task influences TrA contraction during that task.
Design: A case-control cross-sectional study.
Method: We recruited 40 non-pregnant women with persistent pregnancy-related posterior pelvic girdle pain (PGP) and 33 parous women (healthy controls) without PGP. TrA thickness was measured by ultrasound at various levels of bilateral hip adduction, with increments of 20 N from 0 to 140 N. Pain during the tests was registered.
Results: After correction for the level of adduction force, TrA thickness increase during pain-provoking tests of participants with PGP was 6.3 percentage points higher than in their pain-free tests (p = 0.01) and 0.91 percentage points higher than in the pain-free tests of healthy controls (p < 0.01).
Conclusion: TrA contraction in PGP is enhanced when a task provokes pain. These results may have consequences for the treatment of persistent pregnancy-related posterior pelvic girdle pain.
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http://dx.doi.org/10.1016/j.msksp.2017.09.001 | DOI Listing |
J Funct Morphol Kinesiol
December 2024
Department of Physical Therapy, School of Rehabilitation, Biwako Professional University of Rehabilitation, Higashiomi 527-0145, Japan.
Background/objectives: The active straight leg raise requires intricate coordination between the hip, knee, pelvis, and spine. Despite its complexity, limited research has explored the relationship between lower limb raising velocity and trunk muscle motor control during an active straight leg raise in healthy individuals. This study aimed to explore the potential effects of increased lower limb raising velocity on core muscle contractions during active straight leg raises.
View Article and Find Full Text PDFFront Physiol
December 2024
Physiological Laboratory, University of Cambridge, Cambridge, United Kingdom.
Introduction: Intracellular Ca signalling regulates membrane permeabilities, enzyme activity, and gene transcription amongst other functions. Large transmembrane Ca electrochemical gradients and low diffusibility between cell compartments potentially generate short-lived, localised, high-[Ca] microdomains. The highest concentration domains likely form between closely apposed membranes, as at amphibian skeletal muscle transverse tubule-sarcoplasmic reticular (T-SR, triad) junctions.
View Article and Find Full Text PDFCells
December 2024
Institute of Biochemistry II, Jena University Hospital, Friedrich Schiller University Jena, Nonnenplan 2-4, 07743 Jena, Germany.
There is no doubt that the proper development of the heart is important for its correct function, in addition, maturation processes of the heart are crucial as well. The actin-binding protein nexilin seems to take over central roles in the latter processes, as nexilin-deficient mice are phenotypically inconspicuous at birth but die within short time thereafter. Recently, it has been proposed that nexilin plays a role in the formation and function of transverse tubules (T-tubules), which are essential for excitation-contraction coupling in the hearts of mature animals.
View Article and Find Full Text PDFMed J Islam Repub Iran
August 2024
Department of Oral and Maxillofacial Radiology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: There is limited research on the sonographic view of people with skeletal malocclusions. Therefore, this study aimed to evaluate the sonographic findings of the masseter muscle in patients with skeletal malocclusions.
Methods: In this descriptive study, 48 patients aged 15-20 years with skeletal class I, II, and III malocclusions (n = 16) who were referred to Mashhad Dental School for treatment were selected.
Histochem Cell Biol
December 2024
National Research Centre, Kurchatov Institute, 1, Akademika Kurchatova Pl., 123182, Moscow, Russian Federation.
The intercommunication between nerves and muscles plays an important role in the functioning of our body, and its failure leads to severe neuromuscular disorders such as spinal muscular atrophy and amyotrophic lateral sclerosis. Understanding the cellular and molecular mechanisms underlying nerve-muscle interactions and mediating their mutual influence is an integral part of strategies aimed at curing neuromuscular diseases. Here, we propose a novel ex vivo experimental model for the spinal cord (SC) and skeletal muscle interactions which for the first time utilizes only fully formed (but not yet quite functional) postnatal tissues.
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