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An approach to teaching the psychiatric interview.
BMC Med Educ
January 2025
Memorial University of Newfoundland, St. John's, Canada.
The psychiatric interview serves as the cornerstone of psychiatric practice. It is therefore essential that we find effective ways of teaching students how to conduct a psychiatric interview. The present paper arises from two faculty members at Memorial University of Newfoundland and Labrador considering how to improve the quality of teaching of the psychiatric interview to preclerkship undergraduate medical students, before they begin the clinical portion of their training.
View Article and Find Full Text PDFThe MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Int J Biol Macromol
January 2025
Department of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China; Gansu Province Clinical Research Center for Urinary System Disease, Lanzhou, China. Electronic address:
Chemotherapy remains a cornerstone in the treatment of bladder cancer (BLCA); however, the development of chemoresistance substantially limits its efficacy and significantly affects patient survival. Thus, elucidating the molecular mechanisms underlying BLCA chemoresistance is critical to improving patient outcomes. Our study identified MCM6 as an oncogene that facilitates BLCA proliferation and invasion and is linked to cisplatin resistance.
View Article and Find Full Text PDFEvaluating the impact of a hand-crafted 3D-Printed head Model and virtual reality in skull base surgery training.
Brain Spine
December 2024
Department of Neurosurgery, University Hospital of Lausanne and University of Lausanne, 1011, Lausanne, Switzerland.
Introduction: While cadaveric dissections remain the cornerstone of education in skull base surgery, they are associated with high costs, difficulty acquiring specimens, and a lack of pathology in anatomical samples. This study evaluated the impact of a hand-crafted three-dimensional (3D)-printed head model and virtual reality (VR) in enhancing skull base surgery training.
Research Question: How effective are 3D-printed models and VR in enhancing training in skull base surgery?
Materials And Methods: A two-day skull base training course was conducted with 12 neurosurgical trainees and 11 faculty members.
Tamuzimod in patients with moderately-to-severely active ulcerative colitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 induction trial.
Lancet Gastroenterol Hepatol
January 2025
Department of Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Milan, Italy.
Background: Tamuzimod (VTX002) is a selective sphingosine 1-phosphate receptor 1 modulator in development for ulcerative colitis. We aimed to assess the safety and efficacy of tamuzimod in patients with moderately-to-severely active ulcerative colitis.
Methods: This double-blind, randomised, placebo-controlled, phase 2 induction trial was conducted at 122 centres across 15 countries in Asia, Europe, and North America.
Peer review comments: Friend or foe?
J Am Assoc Nurse Pract
January 2025
College of Graduate Nursing, Western University of Health Sciences, Pomona, California.
Peer review is a time-honored cornerstone of publishing. Peer reviewers, often blinded to the author, provide feedback to clarify the manuscript and validate the key messages and sciences. Authors may openly accept the feedback outright and make revisions.
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