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Web-Based Passive Surveillance: Multifactorial Assessment of Sonali Chicken Diseases and Antimicrobial Prescription Pattern in Bangladesh.
Vet Sci
December 2024
Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Zakir Hossain Road, Khulshi, Chattogram 4225, Bangladesh.
Despite the significant growth in Sonali chicken production across Bangladesh, inadequate disease surveillance and control measures along with indiscriminate antimicrobial use remain major challenges to the sector. In this study, we evaluated the disease burden and antimicrobial prescription patterns of Sonali chickens in Bangladesh using a web-based data recording system from 2020 to 2021 and analyzed 1690 cases. The diagnoses recorded in the system were presumptive, as they were based on clinico-epidemiological history, clinical signs, and gross necropsy findings noted by registered veterinarians.
View Article and Find Full Text PDFEpidemiology of Multidrug-Resistant Typhi and Paratyphi Isolated From Stool Culture.
J Trop Med
December 2024
Department of Biochemistry, University of Dschang, Dschang, Cameroon.
Enteric fever is a significant health problem in developing countries caused by serovars Typhi and Paratyphi. Unfortunately, the burden of the disease remains high not only because of the complications related to the disease but also, especially, because of the spread of the strains of resistant to antibiotics. The aim of the present study was to evaluate the antibiotic resistance patterns of Typhi and Paratyphi clinical isolates as well as the risk factors associated with infection.
View Article and Find Full Text PDFCharacterization of serotype 6 strains from geographically diverse low- and middle-income countries.
mBio
January 2025
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Article Synopsis
- Serotype 6 is a common cause of moderate to severe diarrhea but remains understudied, prompting research into its genomic and phenotypic characteristics compared to other serotypes.
- Genomic analyses revealed notable similarities among 6 strains across different regions and timeframes, along with the identification of a potential novel virulence factor and unique patterns of antibiotic susceptibility specific to geographic locations.
- Findings suggest that serotype 6 has distinct genetic and phenotypic traits that could enhance vaccine development and diagnostic tools, which is crucial given the rising incidence of shigellosis, particularly in low- and middle-income countries.
Evaluation of pharmacokinetics and relative bioavailability of pentoxifylline and its metabolite in beagle dogs following different formulations.
Front Pharmacol
November 2024
Department of Clinical Pharmacology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
A single-oral-dose, two-period cross-over study with a 5-day washout period under fed condition was conducted in six beagle dogs to explore the pharmacokinetic characteristics and relative bioavailability between sustained-release (SR) tablets and enteric-coated (EC) tablets of pentoxifylline (PTX) and its metabolite. The results showed that M5 exhibited the highest exposure level, while M1 demonstrated the lowest in both the SR and EC tablet groups. For PTX and M1, T were 0.
View Article and Find Full Text PDFPerianal Paget Disease With an Enteric Phenotype and Associated In-Situ/Dysplastic Glandular Component: Report of a Potentially Novel Entity and Review of the Literature.
Int J Surg Pathol
December 2024
College of Medicine, Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, USA.
Extramammary Paget disease is an uncommon cutaneous malignancy that primarily affects areas rich in apocrine glands. Here, we aim to present an 84-year-old woman with a distinctive perianal neoplastic process comprised of conventional Paget disease with an intertwined in-situ glandular component. Rare foci of glands embedded in pools of mucin were also identified in the most recent excision, consistent with mucinous adenocarcinoma.
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