Survey data often contain many variables. Structural equation modeling (SEM) is commonly used in analyzing such data. With typical nonnormally distributed data in practice, a rescaled statistic T proposed by Satorra and Bentler was recommended in the literature of SEM. However, T has been shown to be problematic when the sample size N is small and/or the number of variables p is large. There does not exist a reliable test statistic for SEM with small N or large p, especially with nonnormally distributed data. Following the principle of Bartlett correction, this article develops empirical corrections to T so that the mean of the empirically corrected statistics approximately equals the degrees of freedom of the nominal chi-square distribution. Results show that empirically corrected statistics control type I errors reasonably well even when N is smaller than 2p, where T may reject the correct model 100% even for normally distributed data. The application of the empirically corrected statistics is illustrated via a real data example.
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http://dx.doi.org/10.1080/00273171.2017.1354759 | DOI Listing |
Gut Microbes
December 2025
Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
The development of fecal microbiota transplantation and defined live biotherapeutic products for the treatment of human disease has been an empirically driven process yielding a notable success of approved drugs for the treatment of recurrent infection. Assessing the potential of this therapeutic modality in other indications with mixed clinical results would benefit from consistent quantitative frameworks to characterize drug potency and composition and to assess the impact of dose and composition on the frequency and duration of strain engraftment. Monitoring these drug properties and engraftment outcomes would help identify minimally sufficient sets of microbial strains to treat disease and provide insights into the intersection between microbial function and host physiology.
View Article and Find Full Text PDFACS Omega
December 2024
Western Australia School of Mines, Minerals, Energy and Chemical Engineering, Curtin University, 26 Dick Perry Avenues, Kensington, 6151 WA, Australia.
Mymensingh Med J
January 2025
Dr Muhammad Rezeul Huq, Classified Specialist, Department of Neurology, Combined Military Hospital, Dhaka, Bangladesh; E-mail:
Wernicke's encephalopathy is a potentially lethal complication of thiamine deficiency which mainly occurs in chronic alcoholic patients. It may occur in other conditions like hyperemesis gravidarum too. Pregnancy may also be complicated with other neurological and cardiac complications.
View Article and Find Full Text PDFSci Rep
December 2024
School of Minging and Geomatics Engineering, Hebei University of Engineering, Handan, 10076, China.
The height of the water-conducting fracture zones (WCFZ) is crucial for ensuring safe coal mining beneath aquifers, particularly considering the secondary development of the WCFZ in upper seams due to repeated mining in close distance coal seams. Accurately predicting this height is essential for mine safety, groundwater protection, and optimal coal resource use. This study compiles extensive measured data from various mining areas in China to analyze the coupling relationship between the WCFZ development height and six influencing factors: mining thickness, mining depth, coal seam spacing, hard rock lithology ratio, and the slope length of working face.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
December 2024
University of Houston, Department of Physics, Houston, Texas, United States.
Purpose: Photon counting detectors offer promising advancements in computed tomography (CT) imaging by enabling the quantification and three-dimensional imaging of contrast agents and tissue types through simultaneous multi-energy projections from broad X-ray spectra. However, the accuracy of these decomposition methods hinges on precise composite spectral attenuation values that one must reconstruct from spectral micro-CT. Errors in such estimations could be due to effects such as beam hardening, object scatter, or detector sensor-related spectral distortions such as fluorescence.
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