In the second part of our Words of Advice on science careers, we bring you the perspectives of established scientists who enjoy successful, fulfilling careers in academia, the patent office and a publishing company. We also get the thoughts of a PhD student on her internship at The FEBS Journal's Editorial Office. Get inspired by these scientists and trace your own path towards a rewarding science career.
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Operando real-space imaging of a structural phase transformation in the high-voltage electrode LiNiMnO.
Nat Commun
December 2024
Department of Materials Science and Engineering, Cornell University, Ithaca, NY, USA.
Discontinuous solid-solid phase transformations play a pivotal role in determining the properties of rechargeable battery electrodes. By leveraging operando Bragg Coherent Diffractive Imaging (BCDI), we investigate the discontinuous phase transformation in LiNiMnO within an operational Li metal coin cell. Throughout Li-intercalation, we directly observe the nucleation and growth of the Li-rich phase within the initially charged Li-poor phase in a 500 nm particle.
View Article and Find Full Text PDFMetaplastic breast cancer (MpBC) is a highly chemoresistant subtype of breast cancer with no standardized therapy options. A clinical study in anthracycline-refractory MpBC patients suggested that nitric oxide synthase (NOS) inhibitor NG-monomethyl-l-arginine (L-NMMA) may augment anti-tumor efficacy of taxane. We report that NOS blockade potentiated response of human MpBC cell lines and tumors to phosphoinositide 3-kinase (PI3K) inhibitor alpelisib and taxane.
View Article and Find Full Text PDFCritical Role of Nanomaterial Mechanical Properties in Drug Delivery, Nanovaccines and Beyond.
Adv Mater
December 2024
School of Chemical Engineering, The University of Adelaide, North Terrace, South Australia, 5005, Australia.
Nanomaterials have become essential in the daily lives, finding applications in food, skincare, drugs, and vaccines. Traditionally, the surface chemistry of nanoparticles (NPs) is considered the key factor in determining their interactions with biological systems. However, recent studies have shown that the mechanical properties of nanomaterials are equally important in regulating nano-bio interactions, though they have often been overlooked.
View Article and Find Full Text PDFEditorial: What is esports performance?
Front Sports Act Living
December 2024
Department of Sports Science and Biomechanics, University of Southern Denmark, Odense, Denmark.
Moving Past the Status Quo: Redefining the Feedback Landscape for Junior Clinician-Educator Career Development.
J Med Educ Curric Dev
December 2024
UT Health Science Center San Antonio, San Antonio, TX, USA.
This perspective piece addresses the challenges junior clinician-educators face as they navigate career development within academic medical centers. In addition to understanding local promotion and tenure processes and seeking mentorship, we argue that faculty feedback is an often neglected, but essential, component in clinician-educator development. We repurpose and use the MISCA model-Message, Implementation, Student, Context, and Agents-as a framework to better understand and improve feedback for faculty.
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