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CKD-Associated Pruritus is Associated with Greater Use of Antidepressants and Anti-pruritus Medications.
Adv Ther
January 2025
CSL Vifor, Glattbrugg, Switzerland.
Introduction: Chronic kidney disease-associated pruritus (CKD-aP) is a common, yet underdiagnosed condition among patients on hemodialysis. Considering the lack of established treatment pathways, we sought to evaluate the use of antidepressant, systemic antihistamines, or gabapentinoid medications among patients with CKD-aP in the year following pruritus assessment.
Methods: We included 6209 patients on hemodialysis in the analysis.
Canonical and noncanonical NOTCH signaling in the nongenetic resistance of cancer: distinct and concerted control.
Front Med
January 2025
Zhejiang University-University of Edinburgh Institute, School of Medicine, Zhejiang University, Jiaxing, 314400, China.
Therapeutic resistance in cancer is responsible for numerous cancer deaths in clinical practice. While target mutations are well recognized as the basis of genetic resistance to targeted therapy, nontarget mutation resistance (or nongenetic resistance) remains poorly characterized. Despite its complex and unintegrated mechanisms in the literature, nongenetic resistance is considered from our perspective to be a collective response of innate or acquired resistant subpopulations in heterogeneous tumors to therapy.
View Article and Find Full Text PDFMonitoring the operational changes in surface reflectances after logging, based on popular indices over Sentinel-2, Landsat-8, and ASTER imageries.
Environ Monit Assess
January 2025
Forest Engineering, Faculty of Forestry, Kastamonu University, Kastamonu, Türkiye.
Revealing the status of forests is important for sustainable forest management. The basis of the concept lies in meeting the needs of future generations and today's generations in the management of forests. The use of remote-sensing (RS) technologies and geographic information systems (GIS) techniques in revealing the current forest structure and in long-term planning of forest areas with multipurpose planning techniques is increasing day by day.
View Article and Find Full Text PDFA knowledge, attitude and practices assessment of control measures for bovine tuberculosis and brucellosis towards a more effective approach to national control programs in South Africa.
Trop Anim Health Prod
January 2025
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, Onderstepoort, University of Pretoria, Pretoria, South Africa.
Bovine brucellosis and bovine tuberculosis are zoonotic diseases with economic and public health importance across the world, especially in developing countries where the diseases are endemic. The diseases are classified as neglected diseases in developing nations with poor resources despite good control measures in some developed countries. The purpose of this study is to assess the knowledge, attitudes and perceptions (KAP) of stakeholders towards control measures for bovine brucellosis (BR) and bovine tuberculosis (bTB) at a livestock-wildlife interface.
View Article and Find Full Text PDFOpening the Cabinets: A Critical Evaluation of Skeletal Teaching Collections in the United States.
Am J Biol Anthropol
January 2025
Mandatory Center of Expertise for the Curation and Management of Archaeological Collections, St. Louis District, U.S. Army Corps of Engineers, St. Louis, Missouri, USA.
The collections of human remains within our university laboratories and classrooms are considered by many to be integral to teaching osteology. However, as an outgrowth of the Western scientific tradition of mind/body dualism, human remains within skeletal teaching collections are often regarded differently than those in museums or applied contexts. From processing to storage, the personhood of each individual becomes abstracted as we purchase, "inherit," handle, organize, and digitally scan their bones for teaching purposes.
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