Rationale: Melanoma in situ of the penis is very rare and there are no clear guidelines for its surgical treatment.

Patient Concerns: The authors describe the case of a 69-year-old man who presented with an asymptomatic brown macula on his glans penis and foreskin that appeared about 8 years earlier, enlarged in the last few months.

Diagnoses: A diagnostic biopsy showed the characteristics of a melanoma in situ.

Interventions: The authors decided to excise the lesion keeping a healthy margin of 1 cm all over around except close to the urethral meatus, where it was impossible, and where only 5 mm of free margin was excised. A full thickness mucosal graft from oral cavity was performed to repair the defect.

Outcomes: No recurrence or metastasis occurred during 50 months after the operation.

Lessons: Considering that at the sixth clinical follow-up the patient was alive and disease free at 50 months after surgery, the chosen treatment has proved successful.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393035PMC
http://dx.doi.org/10.1097/MD.0000000000007652DOI Listing

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