Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12024-017-9913-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cardioprotective potential of tectochrysin against vanadium induced heart damage via regulating NLRP3, JAK1/STAT3 and NF-κB pathway.
J Trace Elem Med Biol
January 2025
Department of Pathology, College of Medicine, King Khalid University, Asir 61421, Saudi Arabia; Department of Forensic Medicine and Clinical Toxicology, Mansoura University, Egypt.
Background: Vanadium (VAN) is a significant trace element, but its higher exposure is reported to cause severe organ toxicity. Tectochrysin (TEC) is a naturally derived flavonoid which demonstrates a wide range of pharmacological properties.
Aim: The current study was planned to assess the cardioprotective potential of TEC against VAN induced cardiotoxicity in rats via regulating biochemical, and histological profile.
Heating up three cold cases in Norway using investigative genetic genealogy.
Forensic Sci Int Genet
December 2024
Department of Forensic Sciences, Oslo University Hospital, Oslo, Norway.
With the advent of commercial DNA databases, investigative genetic genealogy (IGG) has emerged as a powerful forensic tool, rivalling the impact of STR analyses, introduced four decades ago. IGG has been frequently applied in the US and tested in other countries, but never in Norway. Here, we apply IGG to three cold criminal cases and successfully identify the donor of the DNA in two of these cases.
View Article and Find Full Text PDFEvaluation of RMplex system for differentiating father-son pairs using Y-STRs in a Korean population.
Forensic Sci Int Genet
January 2025
Forensic DNA Division, National Forensic Service, Wonju, South Korea. Electronic address:
Y-chromosomal short tandem repeats (Y-STRs) at rapidly mutating (RM) loci have been suggested as tools for differentiating paternally related males. RMplex is a recently developed system that incorporates 26 RM loci and four fast-mutating (FM) loci, targeting 44 male-specific loci. Here, we evaluated the RMplex by estimating Y-STR mutation rates and the overall differentiation rates for 542 Korean father-son pairs, as well as the genetic population values for 409 unrelated males.
View Article and Find Full Text PDFBackground: Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is common in older adults and has been associated with substantial cognitive impairment. However, the association of LATE-NC with brain morphometry has not been thoroughly investigated. In this work, we examined the association of LATE-NC with brain morphometric anomalies using deformation-based morphometry (DBM) in a large community cohort of older adults that came to autopsy (N=897).
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: In the era of disease-modifying treatments for Alzheimer's disease (AD), accurate detection of underlying AD pathology is critical. Blood-based biomarkers for AD are increasingly available, but their diagnostic performance is not well-understood across the spectrum of neurodegenerative disease, especially when AD presents as co-pathology in non-AD syndromes. We investigated the diagnostic performance of three plasma biomarkers (phosphorylated tau 217 [p-tau217], neurofilament light chain [NfL], and glial fibrillary acidic protein [GFAP]) to detect AD, confirmed by autopsy, across 12 clinical neurodegenerative syndromes with various underlying etiologies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!