This case report describes an unusually large facial pilomatrix carcinoma (PC) in a 60-year-old man. This PC had been growing slowly for 11 months and had recently ulcerated. It measured 9 cm × 7 cm × 5 cm. Initial punch biopsy findings were inconclusive. The tumor was excised in total with 5-mm margins in a supra-superficial musculoaponeurotic system plane. The defect was reconstructed with a cervicofacial bilobed rotational advancement flap. Histopathologic findings confirmed the diagnosis of PC. There was no lymph node spread or distant metastasis. The patient recovered with a good esthetic result. This case represents one of the largest facial PCs reported in the literature. Diagnostic challenges are discussed, and the literature is reviewed.
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http://dx.doi.org/10.1016/j.joms.2017.08.010 | DOI Listing |
Arch Dermatol Res
January 2025
Premier Dermatology, Ashburn, VA, USA.
Pilomatrix carcinoma (PC) is a rare malignant adnexal tumor originating from follicular matrix cells primarily impacting Caucasian males. This review provides a comprehensive analysis of scientific literature on PC through an exploration of 206 cases reported between 1980 and 2024. We discuss the epidemiology, clinical presentation, histopathology, and diagnostic challenges of PC, and explore various treatment methods for this rare malignancy as well as their associated outcomes.
View Article and Find Full Text PDFSkinmed
January 2025
Dermatology Department, Miguel Servet Hospital, IIS Aragon, Zaragoza University, Zaragoza, Spain.
A 63-year-old man, with no past medical history, presented with an asymptomatic, progressively evolving polypoid lesion for 2 years in the left ciliary region. Physical examination revealed an exophytic tumor lesion of firm consistency and lobulated surface, with regular and well-defined borders. It measured 2 cm in diameter, and had a brownish-violet coloration with whitish areas (Figure 1).
View Article and Find Full Text PDFInt J Gynecol Pathol
December 2024
Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia.
Int J Dermatol
December 2024
Division of Dermatology, Baylor University Medical Center, Dallas, Texas, USA.
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