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| http://dx.doi.org/10.14503/THIJ-17-6397 | DOI Listing |
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Shorter Premature Atrial Complex Coupling Interval Leads to Mechanical Dysfunction, Fibrosis, and AF in Swine.
JACC Clin Electrophysiol
October 2024
Section of Cardiac Electrophysiology, Division of Cardiology, University of California-San Francisco, San Francisco, California, USA. Electronic address:
Background: We have previously shown that dyssynchronous premature atrial complexes (PACs) from the lateral left atrium (LA) lead to greater atrial mechanical dysfunction, remodeling, and sustained atrial fibrillation (AF) than synchronous PACs from the interatrial septum. However, the impact of PAC coupling interval (CI) on atrial remodeling is unclear.
Objectives: This study sought to explore the effect of PAC CI on atrial mechanics and remodeling in the swine model.
Case Report: Bradycardia in neonatal lupus: differential diagnosis between atrioventricular block and premature atrial contractions with block.
Front Pediatr
July 2024
Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.
Article Synopsis
- * A full-term baby girl diagnosed with neonatal lupus showed symptoms like fetal arrhythmia and bradycardia, with heart irregularities linked to the presence of specific antibodies from her mother.
- * The distinction between high-degree AV block and other issues like bigeminy PACs is crucial, as their management differs significantly; the case might also be the first documented instance of neonatal lupus presenting with atrial tachycardia.
Alterations of Myocardial Mitochondrial Morphology and Function in a Canine Model of Premature Ventricular Contractions-Induced Cardiomyopathy.
Front Biosci (Landmark Ed)
May 2024
Department of Cardiology, Renmin Hospital of Wuhan University, 430060 Wuhan, Hubei, China.
Aims: Changes in myocardial mitochondrial morphology and function in premature ventricular contractions (PVCs)-induced cardiomyopathy (PVCCM) remain poorly studied. Here, we investigated the effects of PVCs with different coupling intervals (CIs) on myocardial mitochondrial remodelling in a canine model of PVCCM.
Methods And Results: Twenty-one beagles underwent pacemaker implantation and were randomised into the sham (n = 7), short-coupled PVCs (SCP, n = 7), and long-coupled PVCs (LCP, n = 7) groups.
Case report: Torsade de pointes induced by the bigeminy result from retrograde ventriculoatrial activation in VVI pacing and resolved by intentional atrial pacing.
Front Cardiovasc Med
May 2023
Department of Cardiology, Peking University First Hospital, Beijing, China.
Introduction: While pacing has been used for long QT syndrome (LQTs), the optimal pacing modality is controversial.
Case: We report a woman with bradycardia and a recently implanted single-chamber pacemaker experienced multiple syncope. No device dysfunction was found.
Tachy-Brady Syndrome in a Schizophrenic Patient: A Case Report.
Cureus
February 2023
Cardiology, Larkin Community Hospital, South Miami, USA.
Article Synopsis
- Tachy-brady syndrome results from sinus node dysfunction, leading to alternating arrhythmias, as seen in a 73-year-old male patient with significant mental health and medical issues who presented with symptoms like catatonia and paranoid delusions.
- During his hospital stay, various arrhythmias were recorded, but the patient remained asymptomatic, confirming the diagnosis of tachy-brady syndrome through telemetry monitoring.
- The treatment plan included beta-blockers and anticoagulation, and ultimately the patient received an implantable dual-chamber pacemaker to manage the risk of both bradyarrhythmias and tachyarrhythmias effectively.
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