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Pre- and Postnatal Lung Development: An Updated Species Comparison. | LitMetric

Pre- and Postnatal Lung Development: An Updated Species Comparison.

Birth Defects Res

Pfizer Global Research & Development, Groton, Connecticut.

Published: November 2017

AI Article Synopsis

Article Abstract

The purpose of this review is to give an outline of respiratory tract morphological and functional development with an emphasis on perinatal and postnatal maturational processes. In view of the rising need for qualitative and quantitative data for the development of pediatric pharmaceuticals, a comparison of the human situation to experimental animal models is made, and functional data as well as suitable models for human airway diseases and functional testing are presented. Birth Defects Research 109:1519-1539, 2017. © 2017 Wiley Periodicals, Inc.

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdr2.1089DOI Listing

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