Purpose: Lung field segmentation for chest radiography is critical to pulmonary disease diagnosis. In this paper, we propose a new deformable model using weighted sparse shape composition with robust initialization to achieve robust and accurate lung field segmentation.
Methods: Our method consists of three steps: initialization, deformation and regularization. The steps of deformation and regularization are iteratively employed until convergence. First, since a deformable model is sensitive to the initial shape, a robust initialization is obtained by using a novel voting strategy, which allows the reliable patches on the image to vote for each landmark of the initial shape. Then, each point of the initial shape independently deforms to the lung boundary under the guidance of the appearance model, which can distinguish lung tissues from nonlung tissues near the boundary. Finally, the deformed shape is regularized by weighted sparse shape composition (SSC) model, which is constrained by both boundary information and the correlations between each point of the deformed shape.
Results: Our method has been evaluated on 247 chest radiographs from well-known dataset Japanese Society of Radiological Technology (JSRT) and achieved high overlap scores (0.955 ± 0.021).
Conclusions: The experimental results show that the proposed deformable segmentation model is more robust and accurate than the traditional appearance and shape model on the JSRT database. Our method also shows higher accuracy than most state-of-the-art methods.
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http://dx.doi.org/10.1002/mp.12561 | DOI Listing |
ACS Infect Dis
January 2025
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, United States.
Developing new classes of drugs that are active against infections caused by is a priority for treating and managing this deadly disease. Here, we describe screening a small library of 20 DNA gyrase inhibitors and identifying new lead compounds. Three structurally diverse analogues were identified with minimal inhibitory concentrations of 0.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
December 2024
Department of Orthodontics, University of Washington, Seattle, USA.
Objective: To evaluate the pharyngeal airway dimensions and regional pharyngeal adipose distribution in the young adult minipig model.
Materials And Methods: Eight 7-8-months-old Yucatan minipigs, half male and female, were sedated and placed prone to scan the pharyngeal region. Magnetic resonance imaging (MRI) was performed using dynamic turbo-field echo (TFE)-sequence with respiratory gating and adipose-weighted sequence.
Ann Thorac Surg Short Rep
September 2024
Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
We report 3 cases of extremely rare familial idiopathic diffuse pulmonary ossification, 2 of 3 received lung transplantation and the other is listed for lung transplantation. The clinical courses of family members varied greatly, and rapid deterioration could occur; therefore, early and close examination is recommended for transplant registration. During transplantation, the lungs appeared and felt exactly like a "pumice stone" and could not collapse, and good visual field was not easily obtained.
View Article and Find Full Text PDFAnn Thorac Surg Short Rep
September 2024
Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
A 54-year-old man underwent right S6 segmentectomy for right lung cancer. After discharge, he presented with fever, hemoptysis, and cough, and computed tomography showed an intermediate bronchus fistula. Because direct closure or bronchoplasty was challenging, a Dumon (Novatech) stent was inserted directly into the fistula from the surgical field and covered with an autologous pericardial patch, pedicled mediastinal fat, and intercostal muscle.
View Article and Find Full Text PDFAsian J Endosc Surg
January 2025
Department of Pediatric Surgery, Research Field in Medical and Health Sciences, Medical and Dental Area, Research and Education Assembly, Kagoshima University, Kagoshima, Japan.
Bronchial atresia (BA) and azygos lobe (AL) are rare congenital pulmonary abnormalities in pediatric patients. We herein report an infantile case of BA combined with AL that was treated with thoracoscopic surgery. The patient was an 8-month-old boy who was preoperatively diagnosed with BA of the right upper lobe (RUL) combined with an AL using fetal magnetic resonance imaging and postnatal enhanced computed tomography.
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