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Vitamin C mesotherapy with microneedling for gingival depigmentation: A case study.
Clin Adv Periodontics
January 2025
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Background: Surgical methods of gingival depigmentation can be challenging, particularly if the gingival phenotype is thin due to the risk of gingival recession and bone exposure. Thus, exploring alternative, non-surgical, minimally invasive treatment modalities is warranted. In dermatology, vitamin C is extensively used for depigmentation and microneedling for collagen induction, with limited literature about its usage for improving gingival esthetics.
View Article and Find Full Text PDFGeneration of a genetically engineered porcine melanoma model featuring oncogenic control through conditional Cre recombination.
Sci Rep
January 2025
Laboratory of Veterinary Embryology and Biotechnology (VETEMBIO), Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.
Article Synopsis
- Melanoma is a severe skin cancer that starts from melanocytes, and existing rodent models have limitations in mirroring human conditions.
- Researchers have created a transgenic pig model that mimics human melanoma using somatic cell nuclear transfer (SCNT), enabling better study of the disease.
- This new model allows for the investigation of melanoma development and response to treatments, providing a significant resource for advancing cancer research and drug testing.
Successful Treatment of Freckles Using a 730-nm Picosecond Laser: A Prospective Study.
Clin Cosmet Investig Dermatol
December 2024
Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.
Objective: Freckles are common hyperpigmented diseases that commonly occur in Caucasians and Asians. Freckles often cause cosmetic and even psychosocial concerns. Various lasers with different wavelengths have been used to treat pigmented spots.
View Article and Find Full Text PDFEpigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota.
Molecules
November 2024
Givaudan Active Beauty, R&D, 31400 Toulouse, France.
(1) Background: Ultraviolet radiation takes part in photoaging and pigmentation disorders on skin. Epigallocatechin gallate (EGCG) is a well-known brightening and photoprotective compound but it faces limitations in terms of stability and solubility. (2) Methods: A more stable and water-soluble glucoside called EGCG-G1 was obtained by enzymatic glucosylation of EGCG.
View Article and Find Full Text PDFManaging neurofibromatosis type I and vision impairment in a resource-limited setting: a case study and multidisciplinary approach.
Ann Med Surg (Lond)
October 2024
College of Medical Sciences, Bharatpur, Chitwan, Nepal.
Article Synopsis
- - Neurofibromatosis type I (NF1) is a genetic disorder that causes benign tumors along nerves, impacting patients' skin and vision, and poses management challenges in areas with limited resources.
- - A 62-year-old woman with NF1 experienced progressive vision loss due to eyelid tumors, which were confirmed as benign nerve tissue upon examination.
- - Effective management in resource-limited settings relied on regular monitoring, patient education, and multidisciplinary care, highlighting the necessity of adaptable approaches to improve patient outcomes and prevent complications like visual impairment.
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