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Objective: To explore how women who used substances during the perinatal period perceived the care they received from interprofessional perinatal care providers.
Design: Appreciative inquiry.
Setting: Interprofessional perinatal care clinic in a large urban tertiary care hospital in Canada.
Supporting Holistic Health and Gestational Diabetes Mellitus Risk Reduction Among Young Native Females Prior to Pregnancy: A Qualitative Exploration.
Int J Environ Res Public Health
December 2024
Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
AI/AN communities are disproportionately impacted by food insecurity and gestational diabetes mellitus (GDM). Decreasing the risk of GDM can interrupt the intergenerational cycle of diabetes in AI/AN families, and can decrease diabetes-related health disparities. The goal of this study was to explore ways of supporting holistic health and reducing the risk of GDM among young American Indian and Alaska Native (AI/AN) females prior to pregnancy.
View Article and Find Full Text PDFInfertility stigma and openness with others are related to depressive symptoms and meaning in life in men and women diagnosed with infertility.
Reprod Health
January 2025
Crean College of Health and Behavioral Sciences, Chapman University, Orange, CA, 92866, USA.
Background: Stigma is the experience of feeling different from socially accepted norms which can lead to personal devaluation or fear of disapproval from others. For men and women experiencing infertility, stigma has been associated with psychological distress, feelings of otherness in relation to people with children, and selective disclosure with others about their infertility challenges. However, there are few studies which examine how infertility stigma and being open with others are related to depressive symptoms and meaning in life for men and women diagnosed with infertility.
View Article and Find Full Text PDFAdapt to survive and thrive: the time is now for adaptive platform trials for preterm birth.
Lancet Child Adolesc Health
February 2025
The Royal Women's Hospital, Melbourne, VIC, Australia; Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, VIC, Australia; Murdoch Children's Research Institute, Melbourne, VIC, Australia.
In this Viewpoint, we discuss the challenges facing perinatal clinical researchers, many of which are unique to this field, and how traditional two-arm randomised trials using frequentist analysis might no longer be fit for purpose for perinatology. We propose a solution: the adoption of adaptive platform trials (APTs) with Bayesian methodology to address perinatal research questions to improve outcomes of preterm birth. APTs use a master protocol as a foundation to efficiently assess multiple interventions simultaneously for a particular disease.
View Article and Find Full Text PDFThe impact of imprecise case definitions in electronic health record research: a melanoma case-study from the Million Veteran Program.
Arch Dermatol Res
January 2025
VA Boston Healthcare System, Boston, MA, USA.
Cases for a disease can be defined broadly using diagnostic codes, or narrowly using gold-standard confirmation that often is not available in large administrative datasets. These different definitions can have significant impacts on the results and conclusions of studies. We conducted this study to assess how using melanoma phecodes versus histologic confirmation for invasive or in situ melanoma impacts the results of a genome-wide association study (GWAS) using the Million Veteran Program.
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