There are no approved treatments for Lassa fever, which is endemic to the same regions of West Africa that were recently devastated by Ebola. Here we show that a combination of human monoclonal antibodies that cross-react with the glycoproteins of all four clades of Lassa virus is able to rescue 100% of cynomolgus macaques when treatment is initiated at advanced stages of disease, including up to 8 d after challenge.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719877 | PMC |
| http://dx.doi.org/10.1038/nm.4396 | DOI Listing |
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