AI Article Synopsis
- Scientists did a big research project using mice to find new genes that help stop tumors from growing.
- They looked at many types of cancer and discovered some genes that are already known and some that are new.
- They tested a few important genes and found that they could be helpful when studying prostate cancer in people.
Article Abstract
We have recently performed a whole-body, genome-wide screen in mice using a single-copy inactivating transposon for the identification of (phosphatase and tensin homolog)-cooperating tumor suppressor genes (TSGs). We identified known and putative TSGs in multiple cancer types and validated the functional and clinical relevance of several promising candidates for human prostate cancer.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540202 | PMC |
| http://dx.doi.org/10.1080/23723556.2017.1325550 | DOI Listing |
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