Pseudotumoral cerebellitis in childhood is an uncommon presentation of cerebellitis mimicking a brain tumor. It often follows an inflammatory or infectious event, particularly due to varicella virus. Patients could have a wide clinical spectrum on presentation. Some patients may be asymptomatic or present at most with mild cerebellar signs, whereas others may suffer severe forms with brainstem involvement and severe intracranial hypertension mimicking tumor warranting surgical intervention. Imaging techniques especially multimodal magnetic resonance imaging represent an interesting tool to differentiate between posterior fossa tumors and acute cerebellitis. We describe a case of pseudotumoral cerebellitis in a 6-year-old girl consequent to mumps infection and review the literature on this rare association.
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| http://dx.doi.org/10.12998/wjcc.v5.i8.340 | DOI Listing |
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Article Synopsis
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- Researchers analyzed cases of 15 children from various clinical centers, finding common symptoms like acute encephalitis and meningitis, and specific MRI patterns in all cases.
- The findings suggest that GFAP antibodies lead to distinct clinical and imaging features, emphasizing the need for testing in pediatric patients with similar symptoms, especially those with brainstem involvement.
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