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A core outcome domain set to assess cutaneous neurofibromas related to neurofibromatosis type 1 in clinical trials.
Br J Dermatol
January 2024
Department of Dermatology.
Article Synopsis
- * A three-phase methodology was used to develop a core outcome domain set for clinical trials targeting NF1-associated cNF, involving a systematic literature review, international consensus process, and voting.
- * The final outcome domains included 'clinical assessment,' 'daily life impact,' 'patient satisfaction,' and 'perception of health,' with consensus reached among stakeholders on how to best evaluate treatment effectiveness for this condition.
A Link Between Inflammatory Mechanisms and Fibromyalgia.
Adv Exp Med Biol
March 2023
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Fibromyalgia (FM) is a condition characterized by chronic widespread pain, which has traditionally been considered psychogenic in nature due to lack of known underlying organic pathophysiology. In more recent years, inflammation of the nervous system has become increasingly recognized as a sign of neuropsychiatric conditions, and this association may enhance our knowledge of conditions such as FM. Emerging evidence has suggested inflammation, particularly neuroinflammation, as a potential contributor underlying the etiology of FM.
View Article and Find Full Text PDFPsychological Dimensions of Palliative Care Consultation: Approaches to Seriously Ill Patients at the End of Life.
J Clin Psychiatry
February 2022
Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Mental health clinicians often hear seriously ill patients ask the unanswerable: Why did this happen? What is the meaning of my suffering? In the inpatient setting, general medical ward, or oncology unit, patients are confronted with their mortality in new, urgent ways. Palliative medicine, or the specialized, comprehensive care of patients facing a life-limiting illness, occupies a unique and liminal space. Although often practiced by clinicians with non-mental health training backgrounds, there exists ample psychological content to be explored in the palliative care encounter.
View Article and Find Full Text PDFC-L Case Conference: A 73-Year-Old Man With "Altered Mental Status" and Agitation.
J Acad Consult Liaison Psychiatry
November 2021
The Avery D. Weisman Psychiatry Consultation Service, Department of Psychiatry, Massachusetts General Hospital, Boston, MA.
Fostering Careers in Medical Education.
Psychiatr Clin North Am
June 2021
Avery D. Weisman Psychiatry Consultation Service, Harvard Medical School, Thomas P. Hackett Center for Scholarship in Psychosomatic Medicine, Office for Clinical Careers, Massachusetts General Hospital, 55 Fruit Street, Warren 606, Boston, MA 02114, USA.
Many careers are available to psychiatrist-educators, and residents should learn about these pathways in addition to developing a core set of teaching skills regardless of their intended career trajectory. Clinician-Educator Programs offer structured opportunities for residents to explore advanced concepts, practice teaching skills, pursue scholarship, and receive mentorship in medical education. Women and persons from minority groups, particularly people of color and gender-diverse individuals, have long been passed over in the promotions process, and correction of these inequities is essential to creating a robust workforce of clinician-educators.
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