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Cranial Tremors in Essential Tremor: Prevalence, Anatomic Distribution and Predictors of Occurrence.
Mov Disord Clin Pract
November 2024
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Background: There are few published data on the prevalence, pattern of anatomic distribution and predictors of various cranial tremors (eg, head, voice, jaw) in essential tremor (ET). Given the high levels of diagnostic misclassification in ET, data on observed clinical patterns would be valuable.
Objectives: To assess the prevalence, pattern of anatomic distribution and predictors of occurrence of cranial tremors in ET.
Tremor-Dominant Movement Disorder in Associated KBG Syndrome.
Tremor Other Hyperkinet Mov (N Y)
September 2024
Institute of Human Genetics, Technical University of Munich, School of Medicine and Health, Munich, Germany.
Article Synopsis
- * A case study of a 24-year-old patient revealed they had a significant tremor disorder, including various types of tremors and additional symptoms like muscle stiffness and coordination issues, alongside some developmental delays and epilepsy.
- * This case underscores the importance of recognizing movement disorders in KBG syndrome, suggesting that genetic testing for pathogenic variants should be considered when diagnosing tremor-related conditions.
The cerebellum computes frequency dynamics for motions with numerical precision and cross-individual uniformity.
Res Sq
July 2024
Department and Graduate Institute of Pharmacology, National Taiwan University College of Medicine, Taipei, Taiwan.
Cross-individual variability is considered the essence of biology, preventing precise mathematical descriptions of biological motion like the physics law of motion. Here we report that the cerebellum shapes motor kinematics by encoding dynamic motor frequencies with remarkable numerical precision and cross-individual uniformity. Using in-vivo electrophysiology and optogenetics in mice, we confirmed that deep cerebellar neurons encoded frequencies via populational tuning of neuronal firing probabilities, creating cerebellar oscillations and motions with matched frequencies.
View Article and Find Full Text PDFThalamic ventral-Oralis complex/rostral zona incerta deep brain stimulation for midline tremor.
J Neurol
October 2024
Neurology Department, S. Anna University Hospital of Ferrara, Via Aldo Moro 8, 44124, Ferrara, Italy.
Background: Midline Tremor is defined as an isolated or combined tremor that affects the neck, trunk, jaw, tongue, and/or voice and could be part of Essential Tremor (ET), or dystonic tremor. The clinical efficacy of deep brain stimulation for Midline Tremor has been rarely reported. The Ventral Intermediate Nucleus and Globus Pallidus Internus are the preferred targets, but with variable outcomes.
View Article and Find Full Text PDFExternal Laryngeal Tremor in Adult-Onset Alexander Disease: A Case Report.
Case Rep Neurol
May 2024
Department of Neurology, Hospital Universitario Marqués de Valdecilla (IDIVAL), University of Cantabria, CIBERNED, Santander, Spain.
Introduction: Alexander disease is caused by mutations in , the glial fibrillary acidic protein gene. External laryngeal tremor has not been reported in adult-onset Alexander disease (AOAxD). The aims of this work were to report one such case and to review the literature on palatopharyngeal tremor and AOAxD.
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