The present study has two major purposes: firstly, to investigate whether the analytical model proposed by Jedwab and Clerc for assessing the mechanical behaviour of an open ends metallic braided stent is applicable to the looped ends stent design and secondly, to compare the response of the two stent designs subjected to radial compression. We use finite element analysis to evaluate the performance of the two braided stents emulating well established designs: WALLSTENT and WallFlex. We validate the WALLSTENT model analytically. We perform a radial crimping simulation and evaluate the radial forces and stresses induced. This study confirms the validity of using the analytical model in the biomechanical analysis of the WALLSTENT design. However, in case of the WallFlex design, a major difference in the results can be observed in the levels of radial forces and wire peak stresses, justifying the decision of using a different alloy in the fabrication of the WallFlex design.
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http://dx.doi.org/10.1016/j.jmbbm.2017.08.025 | DOI Listing |
Int J Mol Sci
January 2025
Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Türkiye.
Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication. This study was conducted to address the limitations of previous experiments, improve methodologies, and precisely determine the biochemical activity conditions of the P2 enzyme in vitro.
View Article and Find Full Text PDFBull Entomol Res
January 2025
Ningxia Academy of Agriculture and Forestry Sciences, Institute of Plant Protection, Yinchuan, China.
Insect odorant-binding proteins (OBPs) are the key proteins in insect olfactory perception and play an important role in the perception and discrimination of insects. is a polyphagous pest and seriously harms the quality and yield of fruits, flowers and crops worldwide. Therefore, the discovery of OBPs has greatly improved the understanding of behavioural response that mediates the chemoreception of .
View Article and Find Full Text PDFJ Am Chem Soc
December 2024
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Shear thinning of associative polymers is tied to bond breakage under deformation and retraction of dangling chains, as predicted by transient network theories. However, an in-depth understanding of the molecular mechanisms is limited by our ability to measure the molecular states of the polymers during deformation. Herein, utilizing a custom-built rheo-fluorescence setup, bond dissociation in model end-linked associative polymers is quantified in real time with nonlinear shear deformation based on a fluorescence quench transition when phenanthroline ligands bind with Ni.
View Article and Find Full Text PDFSoft Matter
November 2024
Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, 19104, USA.
We deploy optical microscopy with and without an applied magnetic field to characterize the three-dimensional morphology and measure the line tension of twist disclinations in twisted nematic liquid crystal (LC) sample cells. Twist disclinations are generated by quenching the LC, 5CB (4-cyano-4'-pentylbiphenyl), into the nematic phase; 5CB is confined between substrates with in-plane anchoring directions perpendicular to one another. The disclinations form loops separating domains of opposite twist handedness.
View Article and Find Full Text PDFJ Mol Biol
February 2025
Department of Computer Science & Software Engineering, The University of Western Australia, Western Australia, Australia. Electronic address:
Determining RNA secondary structure is a core problem in computational biology. Fast algorithms for predicting secondary structure are fundamental to this task. We describe a modified formulation of the Zuker-Stiegler algorithm with coaxial stacking, a stabilising interaction in which the ends of helices in multi-loops are stacked.
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