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Changes in Exposure to Tobacco-Related Harmful and Potentially Harmful Constituents among Adults who Switched Completely from Smoking Cigarettes to Use of the JUUL2 System for Six Days.
Biomarkers
January 2025
Juul Labs, Inc., Washington DC.
Introduction: Adults who switch from smoking cigarettes to use of electronic nicotine delivery systems (ENDS) may reduce their exposure to harmful and potentially harmful constituents (HPHCs). This study assessed changes in exposure to HPHCs, assessed via biomarkers of exposure (BOEs), among adults who switched to a new ENDS product.
Methods: Adults who smoke cigarettes (N = 89) were randomized to: (1) switch completely to using JUUL2 Virginia Tobacco (N = 24) or Polar Menthol (N = 24); (2) continue smoking usual brand (UB) cigarettes (N = 21); or (3) abstain from all tobacco/nicotine products (N = 20) for six days.
Natural terpenes II. Concentration-dependent profile of effects on dynamic organization of biological and model membranes.
Biochem Biophys Res Commun
December 2024
Universidad Nacional de Córdoba, Facultad de Ciencias Exactas, Físicas y Naturales, Departamento de Química, Cátedra de Química Biológica, Córdoba, Argentina; CONICET, Instituto de Investigaciones Biológicas y Tecnológicas (IIByT). Córdoba, Argentina. Electronic address:
Monoterpenes (MTs), the major constituents of plant essential oils, cover a broad spectrum of biological activities through their interaction with biomembranes. MTs are highly hydrophobic substances with a net electrical dipole, but are not clearly amphipathic. As a result, they aggregate at increasing concentrations in aqueous media, and in membrane environments their behavior changes from dynamics modulators to disruptors.
View Article and Find Full Text PDFDynamic effects of ultrasonic treatment on flavor and metabolic pathway of pumpkin juice during storage based on GC-MS and GC-IMS.
Food Chem
December 2024
School of Life Science, Jiangxi Science &Technology Normal University, Nanchang 330013, China.
In this study, the dynamic effects of ultrasonic treatment (0-400 W) on the volatile flavor compounds of pumpkin juice under different storage periods were investigated systematically using a combination of headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) and gas chromatography-ion mobility spectrometry (GC-IMS) techniques. A total of 139 and 46 volatile organic compounds (VOCs) were identified by GC-MS and GC-IMS, respectively. The results indicated that complex changes in volatile components occurred during storage.
View Article and Find Full Text PDFFeatures of disposable e-cigarettes and their association with pricing and consumer preference: Evidence from web data of US online stores.
Addiction
December 2024
Center for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Article Synopsis
- Disposable e-cigarettes are the most popular choice among youth in the US, but there is limited data on their characteristics in the online market.
- The study analyzed 2,320 unique disposable e-cigarette products from five online vape shops, focusing on features like size, pricing, consumer reviews, and key product attributes.
- The findings revealed that products with higher nicotine concentrations received more positive reviews and ratings, while fruit and sweet flavors were preferred over alcohol flavors; additionally, online prices per milliliter were lower compared to in-store prices.
An update of a systematic review and meta-analyses exploring flavours in intervention studies of e-cigarettes for smoking cessation.
Addiction
December 2024
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Aims: To determine patterns of e-cigarette flavour use (sweet, tobacco, menthol/mint) in interventional studies of e-cigarettes for stopping smoking, and to estimate associations between flavours and smoking/vaping outcomes.
Methods: Update of secondary data analyses, including meta-analyses subgrouped by flavour provision and narrative syntheses, incorporating data from January 2004 to February 2024. Eligible studies were identified from a Cochrane review.
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