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The triglyceride-glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with machine learning analysis.
Cardiovasc Diabetol
January 2025
Department of Cardiology, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, People's Republic of China.
Background: Hypertension (HTN) is a global public health concern and a major risk factor for cardiovascular disease (CVD) and mortality. Insulin resistance (IR) plays a crucial role in HTN-related metabolic dysfunction, but its assessment remains challenging. The triglyceride-glucose (TyG) index and its derivatives (TyG-BMI, TyG-WC, and TyG-WHtR) have emerged as reliable IR markers.
View Article and Find Full Text PDFDeterminants of rural practice among a cohort of dental professionals in Australia.
BMC Med Educ
January 2025
La Trobe Rural Health School, La Trobe University, Bendigo, VIC, 3550, Australia.
Background: Most research on tracking practice locations of health students has focused on medical students, particularly the factors influencing their choice to work in rural and remote areas. However, there is limited research on how rural origin and training in regional or rural settings affect the employment destinations of dental and oral health graduates. This paper explores the practice locations of dentistry and oral health therapy (OHT) graduates from rural backgrounds compared to those from metropolitan areas in Australia.
View Article and Find Full Text PDFTransition from the topological to the chaotic in the nonlinear Su-Schrieffer-Heeger model.
Nat Commun
January 2025
Department of Applied Physics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Recent studies on topological materials are expanding into the nonlinear regime, while the central principle, namely the bulk-edge correspondence, is yet to be elucidated in the strongly nonlinear regime. Here, we reveal that nonlinear topological edge modes can exhibit the transition to spatial chaos by increasing nonlinearity, which can be a universal mechanism of the breakdown of the bulk-edge correspondence. Specifically, we unveil the underlying dynamical system describing the spatial distribution of zero modes and show the emergence of chaos.
View Article and Find Full Text PDFQuantifying the shift of public export finance from fossil fuels to renewable energy.
Nat Commun
January 2025
Climate Finance and Policy Group, ETH Zurich, Zurich, Switzerland.
By providing guarantees and direct lending, public export credit agencies (ECAs) de-risk and thus enable energy projects worldwide. Despite their importance for global greenhouse gas emission pathways, a systematic assessment of ECAs' role and financing patterns in the low-carbon energy transition is still needed. Using commercial transaction data, here we analyze 921 energy deals backed by ECAs from 31 OECD and non-OECD countries (excluding Canada) between 2013 and 2023.
View Article and Find Full Text PDFEngaging Patients in Discussions About Medication Deprescribing.
J Gen Intern Med
January 2025
Center for Health Optimization and Implementation Research, VA Boston Healthcare System and VA Bedford Healthcare System, Boston and Bedford, MA, USA.
Background: Deprescribing, intentional medication discontinuation or dose reduction, can reduce potentially inappropriate medication use and medication-related harms. Engaging patients in deprescribing discussions may increase likelihood of deprescribing and promote shared decision-making.
Objective: To examine the impact of patient-directed educational brochures on patient engagement and deprescribing discussions with primary care providers (PCPs).
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