Three studies (Ns = 200, 400, 400) tested the hypothesis that we humans feel disgust when reminded of our animal nature. Participants verbally rated their disgust reaction to pictures of humans engaged in various unpleasant actions. For pictures of events that present danger or suffering, accompanied by an explicit and vivid reminder that animals face the same situation, participants reported fear and sadness rather than disgust. For pictures of events that present a norm violation, an explicit animal reminder (relative to a human picture alone) did not lead to a consequent increment in disgust. For pictures of events that present a physically disgusting contamination, an explicit animal reminder (relative to a human picture alone) led to a decrement in disgust. Thus, not all unpleasant animal reminders are disgusting. Some disgusting things may remind us of our animal nature, but they are not disgusting because they do so. (PsycINFO Database Record
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http://dx.doi.org/10.1037/emo0000365 | DOI Listing |
Liver Int
February 2025
APHP, Hôpital Paul-Brousse, Centre Hépato-Biliaire, Inserm, Unité 1193, Université Paris-Saclay, FHU Hepatinov, Villejuif, France.
Over the past decade, immune checkpoint inhibitors (ICIs) have transformed the treatment of cancer, though they come with the risk of immune-related adverse (irAEs) events such as hepatotoxicity or Immune-mediated Liver Injury from Checkpoint Inhibitors (ILICI). ILICI is a serious irAE that, when severe, requires cessation of ICI and initiation of immunosuppression. Cytotoxic T Lymphocytes (CTLs) play a central role in ILICI; however, they are just part of the picture as immunotherapy broadly impacts all aspects of the immune microenvironment and can directly and indirectly activate innate and adaptive immune cells.
View Article and Find Full Text PDFCureus
December 2024
Critical Care, Captain James A. Lovell Federal Health Care Center, Rosalind Franklin University of Medicine and Science, North Chicago, USA.
This is a case of a young, 20-year-old, male Navy recruit who was admitted to our healthcare facility with intermittent atypical chest pain and limiting exertional symptoms and was diagnosed with myocardial bridging (MB) as the most likely etiology of his chest after the complete cardiac workup, leading to his career limitations due to potential risks. Our patient presented with atypical chest pain and limiting exertional symptoms. Chest pain was non-radiating.
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
Science and Research Centre, School of Electrical Engineering, University of Belgrade, 11000 Belgrade, Serbia.
The selection of an optimal referencing method in event-related potential (ERP) research has been a long-standing debate, as it can significantly influence results and lead to data misinterpretation. Such misinterpretation can produce flawed scientific conclusions, like the inaccurate localization of neural processes, and in practical applications, such as using ERPs as biomarkers in medicine, it may result in incorrect diagnoses or ineffective treatments. In line with the development and advancement of good scientific practice (GSP) in ERP research, this study sought to address several questions regarding the most suitable digital reference for investigating the N400 ERP component.
View Article and Find Full Text PDFVaccines (Basel)
January 2025
Vaccine and Infectious Diseases Organization (VIDO), University of Saskatchewan, Saskatoon, SK S7N 5A2, Canada.
Adjuvants are a diverse group of substances that can be added to vaccines to enhance antigen-specific immune responses and improve vaccine efficacy. The first adjuvants, discovered almost a century ago, were soluble crystals of aluminium salts. Over the following decades, oil emulsions, vesicles, oligodeoxynucleotides, viral capsids, and other complex organic structures have been shown to have adjuvant potential.
View Article and Find Full Text PDFBrain Sci
January 2025
Department of Physical Education, Shanghai Jiao Tong University, Shanghai 200240, China.
: Obesity presents a significant global public health challenge and is associated with declines in both general and food-related inhibitory control, crucial for maintaining a healthy weight and preventing obesity progression. An increasing body of research suggests that acute aerobic exercise may improve inhibitory function. However, the effects and underlying mechanisms of acute aerobic exercise on both general and food-related inhibition in obese adults remain unclear.
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