Psychotropic properties of thyroliberin and melanostatin were studied on the model of timid-defensive behaviour of mice. Oligopeptides increased defensive behaviour and timidity, and decreased intraspecies sociability. GABA deficiency and dopaminergic system blockade increased timid-defensive behaviour of mice. Mobilizing activity of peptides on the agonistic behaviour (aggression and defense) may be explained by their anxiogenic properties.
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