Tubulation of liposomes via the interaction of supramolecular nanofibers.

Chem Commun (Camb)

Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima 739-8527, Japan.

Published: September 2017

AI Article Synopsis

  • The team succeeded in creating tube-like structures from self-assembled lipid membranes, known as liposomes, using nanofibers made of porphyrin J-aggregates.
  • This process was reversible, meaning that the liposomes could revert back from the tubular shape when the porphyrin J-aggregates changed shape.
  • Additionally, the study explored how this tubulation happens and quantified the forces that the porphyrin J-aggregates exerted during the process.

Article Abstract

We achieved tubulation of self-assembled lipid membranes, liposomes, via the interaction of supramolecular nanofibers, porphyrin J-aggregates. This structural change was reversible, and the deformation of the porphyrin J-aggregates caused reconstruction of the liposomes from the tubes. We discussed the tubulation mechanism and calculated the force provided by porphyrin J-aggregates for tubulation.

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Source
http://dx.doi.org/10.1039/c7cc05857hDOI Listing

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