AI Article Synopsis
- The rhizome of Zingiber officinale, known as ginger, is a biennial herb from South Asia used for various clinical issues like constipation, nausea, and cardiovascular problems.
- Ginger's decoction is a staple in Ayurvedic medicine and contains key phytomarkers such as 6-gingerol, 8-gingerol, and 6-shogaol.
- Experimental studies show that while ginger has weak effects on heart function, it significantly impacts smooth muscle, especially in the ileum compared to the aorta.
Article Abstract
The rhizome of the Zingiber officinale Roscoe, a biennial herb growing in South Asia, is commonly known as ginger. Ginger is used in clinical disorders, such as constipation, dyspepsia, diarrhoea, nausea and vomiting and its use is also recommended by the traditional medicine for cardiopathy, high blood pressure, palpitations and as a vasodilator to improve the circulation. The decoction of ginger rhizome is widely used in Ayurvedic medicine. In this papery by high-performance liquid chromatography, we have seen that its main phytomarkers were 6-gingerol, 8-gingerol and 6-shogaol and we report the effects of the decoction of ginger rhizome on cardiovascular parameters and on vascular and intestinal smooth muscle. In our experimental models, the decoction of ginger shows weak negative inotropic and chronotropic intrinsic activities but a significant intrinsic activity on smooth muscle with a potency on ileum is greater than on aorta: EC = 0.66 mg/mL versus EC = 1.45 mg/mL.
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| http://dx.doi.org/10.1080/14786419.2017.1367779 | DOI Listing |
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