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Article Synopsis
- Androgenetic Alopecia (AGA) affects a significant number of men, with 30% experiencing it by age 30 and 50% by age 50.
- A study compared the effectiveness of a combination treatment of topical finasteride 0.25% and minoxidil 5% versus minoxidil 5% alone, involving 164 male participants aged 30-60 with AGA.
- Results showed that 86.7% of the combination treatment group experienced hair regrowth, compared to 69.1% in the minoxidil-only group, indicating the combination therapy is more effective for treating AGA.
Efficacy and safety of combined topical ethinylestradiol with minoxidil versus topical minoxidil in female pattern hair loss. A trichoscopic randomized controlled clinical study.
Clin Exp Dermatol
October 2024
Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Background: Female pattern hair loss (FPHL) is widely common and negatively impacts the quality of life. FPHL is more challenging to treat than male pattern hair loss with minoxidil being the gold standard treatment. Several studies used 17α-estradiol solution for treating FPHL with variable results either alone or combined with minoxidil.
View Article and Find Full Text PDFDickkopf-related Protein 2 Promotes Hair Growth by Upregulating the Wnt/β-catenin Signaling Pathway in Human Dermal Papilla Cells.
Ann Dermatol
October 2024
Department of Dermatology, Inha University School of Medicine, Incheon, Korea.
Background: The Wnt/β-catenin signaling pathway is crucial for the development, initiation, and growth of hair follicles (HFs). The Dickkopf-related protein (DKK) gene family encodes secreted proteins modulating the Wnt/β-catenin signaling pathway. Studies have reported that DKK1 promotes the regression of HFs and serves as a pathogenic mediator in male pattern baldness.
View Article and Find Full Text PDFEstrogen hormone therapy stabilizes lateral hairline in transfeminine patients: Implications for facial feminization surgery.
J Plast Reconstr Aesthet Surg
July 2024
Division of Plastic and Reconstructive Surgery, Department of Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA. Electronic address:
Background: Although several studies report on the suppressing effects of estrogen therapy on facial and body hair in transgender and nonbinary (TGNB) individuals, few studies have elucidated its effects on hairline stability on the scalp. In this study, we assessed the influence of estrogen therapy on forehead length.
Methods: All TGNB patients, aged 30 years or older, assigned male at birth (AMAB) seeking facial feminization surgery were included in the study.
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